Ongoing Estimation of the Epidemic Parameters of a Stochastic, Spatial, Discrete-Time Model for a 1983-84 Avian Influenza Epidemic

Ongoing Estimation of the Epidemic Parameters of a Stochastic, Spatial, Discrete-Time Model for a 1983-84 Avian Influenza Epidemic
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DOI:
10.1637/9429-061710-reg.1
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发表时间:
2011-03-01
期刊:
影响因子:
1.4
通讯作者:
Smith, G.
Smith, G.
中科院分区:
农林科学4区
文献类型:
--
作者:
Rorres, C.;Pelletier, S. T. K.;Smith, G.

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我们制定了一个随机的,空间的,离散时间模型的病毒“易感,暴露,传染,隔离”动物流行病,并将其应用于禽流感疫情在宾夕法尼亚州在1983-84年。使用疫情期间收集的新感染病例数的每周数据,我们发现了病毒潜伏期的估计值和模型传播核内两个参数的值。然后,这些数据在每周渐进的基础上进行折叠,以显示我们的估计如何应用于正在进行的流行病,以产生持续改进的某些流行病参数值。
We formulate a stochastic, spatial, discrete-time model of viral "Susceptible, Exposed, Infectious, Recovered" animal epidemics and apply it to an avian influenza epidemic in Pennsylvania in 1983-84. Using weekly data for the number of newly infectious cases collected during the epidemic, we find estimates for the latent period of the virus and the values of two parameters within the transmission kernel of the model. These data are then jackknifed on a progressive weekly basis to show how our estimates can be applied to an ongoing epidemic to generate continually improving values of certain epidemic parameters.