Effects of body mass index on gastric slow wave: a magnetogastrographic study.

Effects of body mass index on gastric slow wave: a magnetogastrographic study.
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体重指数对胃慢波的影响:胃磁图研究。

DOI:
10.1088/0967-3334/35/2/205
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发表时间:
2014
影响因子:
3.2
通讯作者:
Bradshaw,LA
Bradshaw,LA
中科院分区:
工程技术3区
文献类型:
--
作者:
Somarajan,S;Cassilly,S;Obioha,C;Richards,WO;Bradshaw,LA

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我们同时测量胃磁图(MGG),粘膜肌电图(EMG)和胃电图(EGG)在不同的体重指数(BMI)的人受试者餐前和餐后的胃慢波活动。为了探讨BMI对胃慢波参数的影响,计算每个受试者的BMI,并将其分为两组:BMI≤ 27和BMI> 27的受试者。信号处理与傅立叶谱分析和二阶盲识别(SOBI)技术。我们的研究结果表明,增加BMI不影响信号特征,如频率和振幅的EMG和MGG。另一方面,餐后EGG功率的比较显示,与BMI≤ 27相比,BMI> 27的受试者的统计学显著降低。除了频率和振幅之外,使用来自MGG数据的SOBI计算的传播图使我们能够可视化传播慢波并计算两个BMI组中的传播速度。在我们的研究中,没有观察到速度随BMI或膳食增加而发生显著变化。总之,多通道MGG提供了对不同BMI类别受试者慢波频率、振幅和传播速度的评估,并观察到与BMI无关。
We measured gastric slow wave activity simultaneously with magnetogastrogram (MGG), mucosal electromyogram (EMG) and electrogastrogram (EGG) in human subjects with varying body mass index (BMI) before and after a meal. In order to investigate the effect of BMI on gastric slow wave parameters, each subject's BMI was calculated and divided into two groups: subjects with BMI≤ 27 and BMI> 27. Signals were processed with Fourier spectral analysis and second-order blind identification (SOBI) techniques. Our results showed that increased BMI does not affect signal characteristics such as frequency and amplitude of EMG and MGG. Comparison of the postprandial EGG power, on the other hand, showed a statistically significant reduction in subjects with BMI> 27 compared with BMI≤ 27. In addition to the frequency and amplitude, the use of SOBI-computed propagation maps from MGG data allowed us to visualize the propagating slow wave and compute the propagation velocity in both BMI groups. No significant change in velocity with increasing BMI or meal was observed in our study. In conclusion, multichannel MGG provides an assessment of frequency, amplitude and propagation velocity of the slow wave in subjects with differing BMI categories and was observed to be independent of BMI.
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