NICKEL-DOPED AGAROSE-GEL PHANTOMS IN MR IMAGING
NICKEL-DOPED AGAROSE-GEL PHANTOMS IN MR IMAGING
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DOI：
10.1177/028418519103200519
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发表时间：
1991-09-01
期刊：
影响因子：
1.3
通讯作者：
SJOBERG, S
中科院分区：
文献类型：
--
作者：
CHRISTOFFERSSON, JO;OLSSON, LE;SJOBERG, S
描述了一种用于制造用于磁共振成像的组织模拟体模材料的方法。该材料由掺镍的琼脂糖凝胶组成。通过改变镍和琼脂糖的相对含量，可以独立地改变凝胶的T1和T2值。实际上，可以获得临床上感兴趣的任何T1和T2组合。对其长期稳定性进行了研究，发现其具有良好的稳定性。使用磁共振分析仪估计松弛时间。评估了这些测量的准确性和重复性，发现这些测量是令人放心的。凝胶模体也在磁共振单元中进行了扫描。利用凝胶模体评估反转恢复序列的信号强度，以验证其有用性。将这些测量结果与理论进行了比较，结果吻合很好。此外，还制作了组织等效模。扫描了类似灰质、白质和脑脊液的凝胶。与临床活体扫描以及计算的水平进行了比较。预计这里描述的凝胶模体将在质量保证以及脉冲序列优化中有用。
A method for the production of a tissue-mimicking phantom material for MR imaging is described. The material consists of a nickel-doped agarose gel. The T1 and T2 values of the gel can be varied independently by changing the relative amounts of nickel and agarose. Practically any T1 and T2 combination of clinical interest can be obtained. The long-term stability was studied and found to be good. The relaxation times were estimated using an MR analyzer. The accuracy and the reproducibility of these measurements were evaluated and found to be reassuring. Gel phantoms were also scanned in an MR unit. The signal strength of an inversion recovery sequence was evaluated using the gel phantoms in order to verify their usefulness. These measurements were compared to theory with good agreement. Furthermore, tissue-equivalent phantoms were made. Gels resembling gray matter, white matter, and CSF were scanned. Comparisons with clinical in vivo scans, as well as calculated levels were made. It is anticipated that the gel phantoms described here will be useful in quality assurance as well as in pulse sequence optimization.