Phenotypic correlations of carpal gland diverticular number with production traits and its genome-wide association analysis in multiple pig populations
Phenotypic correlations of carpal gland diverticular number with production traits and its genome-wide association analysis in multiple pig populations
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DOI：
10.1111/age.13407
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发表时间：
2024-02-21
期刊：
影响因子：
2.4
通讯作者：
Huang，Lusheng
中科院分区：
文献类型：
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作者：
Cui，Dengshuai;Li，Longyun;Huang，Lusheng
猪腕腺在领土识别、繁殖行为和信息交换中起着重要作用；然而，它们对生产性状的影响和潜在的遗传机制尚不清楚。本试验选用6个猪群的1028头猪，计算左腿（CGDNL）和右腿（CGDNR）的腕腺憩室数（cgdn），并对其胴体性状和肉质性状进行评价。不同群体间CGDN差异显著，荔枝黑猪CGDN低于巴马香品种。性别差异也显著，男性憩室数多于女性（p≤0.0391）。且数量不对称，cgdnr显著高于CGDNL。值得注意的是，cgdn在表型和遗传上均与24 h pH、24 h肉色评分、24 h大理石纹评分、表型上的脂肪含量、水分含量、钠盐含量和饱和脂肪酸含量显著相关。此外，全基因组关联分析发现了7个与cgdn相关的snp，其全基因组显著性水平为5%，全部位于1号染色体1.78 Mb （35.347-37.129 Mb）区域。CNC10010837和CNC10010840是最高的snp，它们对cgdnr的加性效应为0.789±0.120,p= 8.31E‐10。这些发现为猪腕腺的功能和潜在的遗传机制提供了重要的见解。
Pig carpal glands play crucial roles in territorial recognition, reproductive behavior, and information exchange; however, their effects on production traits and underlying genetic mechanisms remain unclear. In this study, 1028 pigs from six populations were counted for the carpal gland diverticular numbers (CGDNs) on the left (CGDNL) and right (CGDNR) legs, and their carcass and meat quality traits were assessed. The CGDNs were significantly different among the populations, and Licha Black pigs had a lower CGDN than the Bama Xiang breed. It was also significantly different between sexes, with males having more diverticula than females (p≤ 0.0391). Moreover, the number was asymmetric, with CGDNRbeing significantly higher than CGDNL. Notably, CGDNs was significantly correlated with each other in phenotype and genetics and with 24‐h pH, 24‐h meat color score, 24‐h marbling score, fat content, moisture content, sodium salt content, and saturated fatty acid content in phenotype. Furthermore, genome‐wide association analyses identified seven SNPs in association with CGDNs at a 5% genome‐wide significance level, all of which were located in a 1.78‐Mb (35.347–37.129 Mb) region on chromosome 1. CNC10010837 and CNC10010840 were the top SNPs: both had an additive effect of 0.789 ± 0.120 on CGDNRwithp= 8.31E‐10. These findings provide important insights into the functions and underlying genetic mechanisms of swine carpal glands.