NF-κB guides the survival and differentiation of developing lymphocytes
NF-κB guides the survival and differentiation of developing lymphocytes
复制标题
DOI：
10.1038/sj.cdd.4401894
复制
发表时间：
2006-05-01
影响因子：
12.4
通讯作者：
Siebenlist, U
中科院分区：
文献类型：
--
作者：
Claudio, E;Brown, K;Siebenlist, U
本文讨论了核因子 κB 如何通过协助淋巴细胞走向成熟并确保其在关键阶段的存活来指导淋巴细胞发育的关键问题。核因子 κB 还可以帮助淋巴细胞做好对病原体的反应，并通过塑造多种细胞类型的反应来激活宿主防御。
The article discusses key issues concerning how nuclear factor κB guides the development of lymphocytes by assisting in their progression towards maturity and ensuring their survival at critical stages. Nuclear factor κB also prepares the lymphocytes to ably respond to pathogens and activates host defenses by shaping the response of many cell types.