Pregnancy in a quadriplegic patient treated with continuous intrathecal baclofen infusion to manage her severe spasticity. Case report
Pregnancy in a quadriplegic patient treated with continuous intrathecal baclofen infusion to manage her severe spasticity. Case report
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一名四肢瘫痪患者怀孕后接受持续鞘内注射巴氯芬治疗以控制严重痉挛。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
J. Verhagen
中科院分区：
文献类型：
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作者：
E. Delhaas;J. Verhagen
一份关于使用植入式药物输送系统（Synchromed，（R）Medtronic，USA）接受高剂量1000 mcg/24小时持续鞘内巴氯芬输注治疗的四肢瘫痪患者妊娠的报告。痉挛可以管理到怀孕的第35周。然而，子宫收缩引起巨大的痉挛症状，我们，即使最大值的痉挛量表，不能分类。痉挛的复发与自主神经失调有关。持续硬膜外输注布比卡因（11.25 mg/h）可达到充分松弛，并通过初次剖腹产终止妊娠。出生了一个健康的女孩（2040 g，Apgar 9和10）。
A report on pregnancy in a quadriplegic patient treated with a high dose of 1000mcg/24h continuous intrathecal baclofen infusion using an implanted drug delivery system (Synchromed,(R) Medtronic, USA). Spasticity could be managed up to the 35th week of gestation. However, uterine contractions evoke enormous spastic symptoms which we, even with maximum values of the spasticity scales, could not classify. The recurrence of spasticity was associated with autonomic dysregulation. With continuous epidurally infused bupivacaine (11.25 mg/h) adequate relaxation could be reached and gestation was terminated by a primary caesarean section. A healthy girl was born (2040 g, Apgar 9 and 10).