The evolution of host specialization in an insect pathogen
The evolution of host specialization in an insect pathogen
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DOI：
10.1111/evo.14594
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发表时间：
2022-08-22
期刊：
影响因子：
3.3
通讯作者：
Boots，Mike
中科院分区：
文献类型：
--
作者：
Visher，Elisa;Uricchio，Lawrence;Boots，Mike
生物伙伴之间的生态位宽度共同进化是多样性和共存理论的基础，并影响宿主-寄生虫系统中疾病的出现和传播模式。尽管有这些广泛的影响，我们仍然不完全了解寄生虫传染性的广度是如何演变的，任何相关成本的性质，或专业化的遗传基础。在这里，我们连续传代了一种颗粒病病毒在其多个自交种群的间隔性弯孢霉寄主上，以探索特化的动态和结果。特别是，我们收集了表型和遗传数据的时间序列，以探索整个实验进化过程中宿主基因型专门化的动态，并检查两个适合度成分。我们发现，Plodia间点间颗粒病病毒不断进化，并在整体专业化程度上增加，但我们的两个适应度成分独立进化，因此品系可以专门研究生产力或传染性。此外，我们发现，在我们的实验中，专门化是一种高度多基因的特征，最好的解释是进化机制的组合。这些结果对于理解宿主-寄生虫相互作用中专业化的演变及其对共存、多样化和传染病管理的更广泛的影响是重要的。
Niche breadth coevolution between biotic partners underpins theories of diversity and co-existence and influences patterns of disease emergence and transmission in host-parasite systems. Despite these broad implications, we still do not fully understand how the breadth of parasites’ infectivity evolves, the nature of any associated costs, or the genetic basis of specialization. Here, we serially passage a granulosis virus on multiple inbred populations of itsPlodia interpunctellahost to explore the dynamics and outcomes of specialization. In particular, we collect time series of phenotypic and genetic data to explore the dynamics of host genotype specialization throughout the course of experimental evolution and examine two fitness components. We find that thePlodia interpunctellagranulosis virus consistently evolves and increases in overall specialization, but that our two fitness components evolve independently such that lines can specialize in productivity or infectivity. Furthermore, we find that specialization in our experiment is a highly polygenic trait best explained by a combination of evolutionary mechanisms. These results are important for understanding the evolution of specialization in host-parasite interactions and its broader implications for co-existence, diversification, and infectious disease management.