Quality of life and recurrence concern in survivors of head and neck cancer
Quality of life and recurrence concern in survivors of head and neck cancer
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DOI：
10.1097/00005537-200006000-00003
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发表时间：
2000-06-01
期刊：
影响因子：
2.6
通讯作者：
Layde, PM
中科院分区：
文献类型：
--
作者：
Campbell, BH;Marbella, A;Layde, PM
目的/假设：研究设计：邮寄问卷，对头颈部癌症3年生存者队列的持续生活质量（QOL）问题和长期治疗效果进行评价。研究方法：将华盛顿大学生活质量（UWQOL）量表、头颈癌体能状态量表（PSS-HN）、癌症治疗功能评估（FACT）量表和癌症治疗头颈部功能评估（FACT-ICN）量表的问卷和当地准备的问题发送给111例3年无疾病生存者。分析阶段、部位、治疗类型、手术和癌症关注对生活质量的影响，收集当前吸烟信息。结果：72名幸存者完成了问卷调查。晚期患者在毁容、咀嚼能力、言语和在公共场所进食方面的生活质量评分较低，生活质量评分不随初始肿瘤部位而变化。在疼痛、毁容、咀嚼和言语领域，单独接受放疗的患者的QOL评分在统计学上优于接受手术/放疗联合治疗的患者。喉切除术和复合切除术的幸存者报告的生活质量评分低于单纯放疗的患者。大约一半的长期幸存者对癌症的关注程度较低。癌症的担忧与持续的疼痛、毁容和在公共场合进食的限制有关。四分之三的烟草使用者在问卷调查时已经戒烟。尽管如此，患者并不完全相信烟草导致了他们的癌症。结论：头颈部癌症的长期存活者在完成治疗后生活质量得到了很好的改善。影响在需要联合手术/放射治疗的幸存者中最为明显。在大约一半的幸存者中，癌症的关注程度仍然很低。许多癌症幸存者成功戒烟。
Objectives/Hypothesis: A cohort of 3-year survivors of head and neck cancer was evaluated for persistent quality of life (QOL) concerns and long-term treatment effects, Study Design: Mailed questionnaire. Methods: The questionnaire with the University of Washington Quality of Life (UWQOL) scale, the Performance Status Scale for Head and Neck Cancer (PSS-HN), the Functional Assessment of Cancer Therapy (FACT) scale, and the Functional Assessment of Cancer Therapy Head and Neck (FACT-ICN) scale and locally prepared questions was sent to 111 3-year disease-free survivors. Analysis was performed to statistically evaluate the effect of stage, site, treatment type, surgery, and cancer concern on QOL, Current smoking information was gathered. Results: Seventy-two survivors completed the questionnaire. Advanced stage was correlated with lower QOL scores in the domains of disfigurement, chewing ability, speech, and eating in public, QOL scores did not vary by initial tumor site. Patients treated with irradiation alone had statistically better QOL scores than those treated with combined surgery/radiation therapy in the pain, disfigurement, chewing, and speech domains. Laryngectomy and composite resection survivors reported lower QOL scores than patients treated with irradiation alone. A low level of cancer concern persisted in about half of the long-term survivors. Cancer concern was associated with continued pain, disfigurement, and limitations on eating in public, Three-quarters of the tobacco users had quit by the time of the questionnaire. Nevertheless, the patients were not thoroughly convinced that tobacco had caused their cancer. Conclusions: Long-term survivors of head and neck cancer experience QOL effects well after completion of treatment. Effects are most pronounced in survivors who required combined surgery/radiation therapy. Continuing low levels of cancer concern persist in about half of the survivors. Many cancer survivors successfully quit smoking.