Distribution and origin of TRPV1 receptor-containing nerve fibers in the dura mater of rat

Distribution and origin of TRPV1 receptor-containing nerve fibers in the dura mater of rat
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DOI:
10.1016/j.brainres.2007.07.068
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发表时间:
2007-10-10
期刊:
影响因子:
2.9
通讯作者:
Suzuki, Norihiro
Suzuki, Norihiro
中科院分区:
医学3区
文献类型:
--
作者:
Shimizu, Toshihiko;Toriumi, Haruki;Suzuki, Norihiro

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We examined the distribution and origin of the nerve fibers innervating the dura mater of the rat that show immunoreactivity for the TRPV1 receptor (TRPV1-IR). Nearly 70% of the nerve fibers showing TRPV1-IR in the dura mater also exhibited CGRP-IR. Using a combination of immunohistochemistry and a retrograde tracer technique, we detected tracer accumulation in 0.6% of the neurons in the trigeminal ganglion and a few neurons in the dorsal root ganglion; half of the neurons in the trigeminal ganglion were small-and medium-sized (