Sleep-mediated memory consolidation depends on the level of integration at encoding
Sleep-mediated memory consolidation depends on the level of integration at encoding
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DOI：
10.1016/j.nlm.2016.11.019
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发表时间：
2017-01-01
影响因子：
2.7
通讯作者：
Schoenauer, Monika
中科院分区：
文献类型：
--
作者：
Himmer, Lea;Mueller, Elias;Schoenauer, Monika
有强有力的证据表明睡眠有助于陈述性记忆巩固。已提出将新获得的记忆整合到现有的新皮质知识网络中以形成这种效应。在这里，我们测试了当显式学习或使用快速映射策略时，睡眠对单词-图片关联的记忆保留是否有不同的影响。快速映射是一种偶然的学习形式，它将新信息引用到现有知识，并可能在编码过程中允许新皮质整合。如果将信息整合到新皮质网络中是睡眠依赖性记忆巩固的主要功能，那么通过快速映射学习的材料从睡眠中获益应该较少。支持这一观点的是，我们发现睡眠对显式习得的关联具有保护作用。相比之下，通过快速映射学习到的关联记忆不会从睡眠中受益，并且无论学习后是睡眠还是清醒，记忆都保持稳定。因此，我们的结果表明，睡眠介导的巩固的需要取决于用于学习的策略，因此可能与编码过程中新获得的记忆的整合水平有关。 (C) 2016 Elsevier Inc. 保留所有权利。
There is robust evidence that sleep facilitates declarative memory consolidation. Integration of newly acquired memories into existing neocortical knowledge networks has been proposed to underlie this effect. Here, we test whether sleep affects memory retention for word-picture associations differently when it was learned explicitly or using a fast mapping strategy. Fast mapping is an incidental form of learning that references new information to existing knowledge and possibly allows neocortical integration already during encoding. If the integration of information into neocortical networks is a main function of sleep-dependent memory consolidation, material learned via fast mapping should therefore benefit less from sleep. Supporting this idea, we find that sleep has a protective effect on explicitly learned associations. In contrast, memory for associations learned by fast mapping does not benefit from sleep and remains stable regardless of whether sleep or wakefulness follows learning. Our results thus indicate that the need for sleep-mediated consolidation depends on the strategy used for learning and might thus be related to the level of integration of newly acquired memory achieved during encoding. (C) 2016 Elsevier Inc. All rights reserved.