Autophagy during conidiation, conidial germination and turgor generation in Magnaporthe grisea
Autophagy during conidiation, conidial germination and turgor generation in Magnaporthe grisea
复制标题
稻瘟病菌分生孢子形成、分生孢子萌发和膨压生成过程中的自噬
DOI：
10.4161/auto.4339
复制
发表时间：
2007-09-01
期刊：
影响因子：
13.3
通讯作者：
Lin, Fu-Cheng
中科院分区：
文献类型：
--
作者：
Liu, Xiao-Hong;Lu, Jian-Ping;Lin, Fu-Cheng
自噬是一种普遍存在的进化保守的过程，存在于所有真核细胞中，允许旧蛋白质和细胞器的降解和循环。L过程饥饿可以诱导自噬，自噬途径是饥饿状态下细胞功能的必需品。在稻瘟病菌中，饥饿是胚管顶端分化为附着胞的关键诱导因素之一。鉴于稻瘟菌作为寄主-病原菌相互作用的主要模型的重要性，通过其在细胞器和蛋白质周转中的作用，自噬在真菌发育、附着胞膨大发生和稻瘟病菌致病性中的作用是一个非常重要的课题。
Autophagy is a ubiquitous and evolutionarily conserved process found in all eukaryotic cells that allows for the degradation and recycling of old proteins and organelles. l process Starvation can induce autophogy, and autophagic pathway is an essentia for cellular function under starvation. In Magnaporthe grisea, starvation is one of the key induced factors for the germ tube tip to differentiate into an appressorium. Considering the importance of the rice blast fungus as a primary model for host-pathogen interaction, the role of autophagy in fungal development, appressorium turgor generation and pathogenicity of M. grisea via its role in organelle and protein turnover is a very significant subject.