AGE-RELATED-CHANGES IN CAROTID-ARTERY WALL PROPERTIES IN MEN
AGE-RELATED-CHANGES IN CAROTID-ARTERY WALL PROPERTIES IN MEN
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DOI：
10.1016/0301-5629(86)90218-8
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发表时间：
1986-06-01
影响因子：
2.9
通讯作者：
HOEKS, APG
中科院分区：
文献类型：
--
作者：
RENEMAN, RS;VANMERODE, T;HOEKS, APG
在80名假定健康的志愿者中研究了颈总动脉扩张性和横截面顺应性随年龄的变化，年龄在20至69岁之间。根据收缩期动脉直径相对于动脉脉压标准化的相对增加来评估扩张性。横截面顺应性通过将扩张性乘以动脉直径获得。应用高分辨率多门脉冲多普勒系统在线记录心动周期中颈总动脉相对内径的变化。动脉直径的评估从宽度的速度曲线，这也可以记录在线与该系统。动脉脉压由肱动脉袖带血压测量值确定。颈总动脉的扩张性和横截面顺应性都随着年龄的增长而线性下降，从第三个十年开始。后一个参数的减少不太明显，可能是由于动脉直径随年龄增长而增加。
Changes in distensibility and cross-sectional compliance of the common carotid artery with age were studied in 80 presumed healthy volunteers, varying in age between 20 and 69 y. The distensibility was assessed from the relative increase in arterial diameter during systole normalized with respect to the arterial pulse pressure. The cross-sectional compliance was obtained by multiplying the distensibility by the arterial diameter. The relative diameter changes of the common carotid artery during the cardiac cycle were recorded on-line with a high resolution multigate pulsed Doppler system. The arterial diameter was assessed from the width of the velocity profiles which can also be recorded on-line with this sytem. Arterial pulse pressure was determined from brachial artery cuff blood pressure measurements. Both distensibility and cross-sectional compliance of the common carotid artery decreased linearly with age, starting in the third age decade. The reduction in the latter parameter was less pronounced, probably as a consequence of an increase in arterial diameter with age.