Bandage: interactive visualization of de novo genome assemblies
Bandage: interactive visualization of de novo genome assemblies
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DOI：
10.1101/018333
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发表时间：
2015-04
期刊：
影响因子：
5.8
通讯作者：
R. Wick;Mark B. Schultz;J. Zobel;K. Holt
中科院分区：
文献类型：
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作者：
R. Wick;Mark B. Schultz;J. Zobel;K. Holt
虽然从头组装图包含组装的重叠群（节点），但用户难以访问这些重叠群（边缘）之间的连接。Bandage（一个用于轻松导航从头组装图的生物信息学应用程序）是一个可视化连接组装图的工具。用户可以放大到图形的特定区域，并通过移动节点、添加标签、更改颜色和提取序列来与图形进行交互。可以在Bandage GUI中执行BLAST搜索，命中结果在图表中突出显示。通过显示重叠群之间的连接，Bandage为分析从头组装提供了新的可能性，而这是通过单独调查重叠群不可能实现的。源代码和二进制文件可以在https://github.com/rrwick/Bandage上免费获得。绷带是在C++中实现的，并在Linux、OS X和Windows上受支持。联系rrwick@gmail.com补充信息完整的功能列表和屏幕截图可在生物信息学在线和http://rrwick.github.io/Bandage。
Summary While de novo assembly graphs contain assembled contigs (nodes), the connections between those contigs (edges) are difficult for users to access. Bandage (a Bioinformatics Application for Navigating De novo Assembly Graphs Easily) is a tool for visualising assembly graphs with connections. Users can zoom in to specific areas of the graph and interact with it by moving nodes, adding labels, changing colours and extracting sequences. BLAST searches can be performed within the Bandage GUI and the hits are displayed as highlights in the graph. By displaying connections between contigs, Bandage presents new possibilities for analysing de novo assemblies that are not possible through investigation of contigs alone. Availability and implementation Source code and binaries are freely available at https://github.com/rrwick/Bandage. Bandage is implemented in C++ and supported on Linux, OS X and Windows. Contact rrwick@gmail.com Supplementary information A full feature list and screenshots are available at Bioinformatics online and http://rrwick.github.io/Bandage.