Computed tomographic findings of large cell neuroendocrine carcinoma of the lung
Computed tomographic findings of large cell neuroendocrine carcinoma of the lung
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DOI：
10.1016/j.clinimag.2007.04.027
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发表时间：
2007-11-01
期刊：
影响因子：
2.1
通讯作者：
Kato, Hairubumi
中科院分区：
文献类型：
--
作者：
Akata, Soichi;Okada, Shinya;Kato, Hairubumi
我们的研究目的是描述大细胞神经内分泌癌（LCNEC）的计算机断层扫描（CT）表现，并将放射学和病理学表现联系起来。我们回顾了36例LCNEC切除标本的CT表现[包括29例高分辨率计算机断层扫描（HRCT）表现]。有33名男性（92%），30名患者有吸烟史（83%）。仅1例为中央型。纵隔或肺门淋巴结肿大12例（33%），但只有1例表现为巨大淋巴结肿大。LCNEC的HRCT表现包括边缘不规则（66%）、周围肺气肿（41%）、切迹（38%）、钙化（21%）和胸膜凹陷（24%）。我们的研究表明，LCNEC的CT图像通常显示位于周围，膨胀性生长，边缘不规则的肺肿块，有或没有钙化，没有巨大的淋巴结肿大。虽然LCNEC的CT图像类似于鳞状细胞癌，但空洞并不常见。根据CT表现，LCNEC不能与低分化腺癌或不典型类癌鉴别。(C)2007年爱思唯尔公司All rights reserved.
The purpose of our study was to describe the computed tomography (CT) findings of large cell neuroendocrine carcinoma (LCNEC) and to correlate radiological and pathological findings. We reviewed the CT findings of 36 patients [including the high-resolution computed tomography (HRCT) findings of 29 patients] with resected LCNEC specimens. There were 33 men (92%), and 30 patients had a smoking history (83%). Only one case was of the central type. Mediastinal or hilar lymphadenopathy was seen in 12 (33%), but only one showed bulky lymphadenopathy. The HRCT findings of LCNEC consisted of irregular margins (66%), surrounding emphysema (41%), notching (38%), calcifications (21%), and pleural indentation (24%). Our study indicates that the CT image of LCNEC generally shows a peripherally located, expansively growing, irregularly margined pulmonary mass, with or without calcification, and without bulky lymph adenopathy. While the CT image of LCNEC resembles that of squamous cell carcinoma, cavitation is infrequent. LCNEC cannot be differentiated from poorly differentiated adenocarcinoma or atypical carcinoid on the basis of CT findings. (C) 2007 Elsevier Inc. All rights reserved.