Angiogenic potential of the avian somite.
Angiogenic potential of the avian somite.
复制标题
鸟类体节的血管生成潜力。
DOI：
10.1002/aja.1002020208
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Christ,B
中科院分区：
文献类型：
--
作者：
Wilting,J;Brand-Saberi,B;Huang,R;Zhi,Q;Kontges,G;Ordahl,CP;Christ,B
我们研究了鹌鹑和鸡胚同位移植的躯干不分节近轴中胚层和上皮体节的血管生成潜力。再孵育1-6天后，用QH-1抗体对移植物的鹌鹑内皮细胞进行染色。发现不分节的近轴中胚层和上皮体节的所有部分含有成血管细胞，其发育成QH-1阳性内皮细胞。这些细胞被整合到宿主血管的内层，例如神经周围血管丛和主动脉的背侧支。关于来自体节不同部分的内皮细胞的位置，存在一定的偏好。腹侧体节的成血管细胞主要存在于腹外侧血管中。来自背内侧象限的在背部的真皮中形成血管，而来自背外侧象限的可以在腹外侧体壁和翅膀中找到。除了背侧神经束血管丛外，成血管细胞不穿过身体的正中面。这表明，虽然成血管细胞广泛迁移，但躯干中的血管系统是双侧性的。脊索是否在这种双边关系的建立中发挥作用还有待研究。© 1995 Wiley利斯公司
We have studied the angiogenic potential of the unsegmented paraxial mesoderm and epithelial somites of the trunk with homotopical grafts between quail and chick embryos. Quail endothelial cells of the grafts were stained with the QH‐1 antibody after 1–6 days of reincubation. The unsegmented paraxial mesoderm and all parts of the epithelial somite were found to contain angioblasts which develop into QH‐1 positive endothelial cells. These cells are incorporated into the lining of the host's blood vessels such as the perineural vascular plexus and the dorsal branches of the aorta. There is a certain preference as concerns the location of endothelial cells derived from different parts of the somites. Angioblasts from ventral somite halves are mainly found in ventrolateral blood vessels. Those from dorsomedial quadrants form vessels in the dermis of the back, and those from dorsolateral quadrants can be found in the ventrolateral body wall and the wing. With the exception of the dorsal perineural vascular plexus, angioblasts do not cross the median plane of the body. This shows that, although angioblasts migrate extensively, there is bilaterality of the vascular system in the trunk. It remains to be studied whether the notochord plays a role in the establishment of this bilaterality. © 1995 Wiley‐Liss, Inc.