Squamous carcinoma of the breast.
Squamous carcinoma of the breast.
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乳腺癌鳞状细胞癌。
DOI：
10.1093/ajcp/55.4.410
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发表时间：
1971
影响因子：
3.5
通讯作者：
H. Enterline
中科院分区：
文献类型：
--
作者：
J. Cornog;J. Mobini;E. Steiger;H. Enterline
本文介绍了 24 例以鳞状分化为显着组织学特征的乳腺癌病例。肿瘤通常相对较大，并且经常形成内衬鳞状上皮的大中央囊肿。发现高度不同程度的鳞状细胞分化与腺癌、间变性癌和髓样癌以及一种源自叶状囊肉瘤的鳞状细胞癌有关。两种癌明显属于纯鳞状癌。 1965 年之前接受治疗的 14 名患者的五年生存率为 50%，接近同期接受治疗的所有乳腺癌病例的五年生存率。结论是，虽然单纯的乳腺鳞状癌很少见，但与其他类型乳腺癌相关的不同程度的鳞状分化并不少见，并且这种分化对临床病程或生存没有明显影响。
Twenty-four cases of carcinoma of the breast in which squamous differentiation was a prominent histologic feature are presented. The tumors were often relatively large and frequently formed large central cysts lined by squamous epithelium. Highly varied degrees of squamous differentiation were found in association with adenocarcinomas, anaplastic and medullary carcinomas, and one squamous carcinoma originating in a cystosarcoma phylloides. Two carcinomas were of an apparently pure squamous type. The five-year survival rate for 14 patients treated before 1965, 50%, is close to that achieved for all cases of carcinoma of the breast treated in the same period. It is concluded that although pure squamous carcinomas of the breast are rare, various degrees of squamous differentiation in association with other types of carcinoma of the breast are not infrequent, and that such differentiation has no apparent effect on clinical course or survival.