Primary infantile glaucoma in an Australian population
Primary infantile glaucoma in an Australian population
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DOI：
10.1046/j.1442-9071.2004.00750.x
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发表时间：
2004-01-01
影响因子：
4
通讯作者：
Mackey, DA
中科院分区：
文献类型：
--
作者：
MacKinnon, JR;Giubilato, A;Mackey, DA
背景：原发性婴儿青光眼很少出现，但可导致严重的视力疾病。相对于原发性和继发性青光眼混合人群或伴有小梁发育不全和虹膜小梁发育不全的青光眼合并组，单纯婴幼儿原发性青光眼的临床特征和视力结果的资料很少。方法：我们使用皇家儿童医院眼科诊断编码数据库，对1980年至2000年间澳大利亚东南部的原发性婴儿青光眼儿童进行回顾性分析。结果：发现51例原发性婴儿青光眼（83只眼）。这相当于估计发病率约为每3万例分娩中有1例。就诊时的平均+/- SD年龄为135 +/- 84天。10.8%的患者被诊断为“烧坏”病（无眼压升高的大角膜）。巩膜切开术是最常见的手术方式（占72只眼的69.4%）。74%的眼睛成功进行了一次或两次的性腺切开术。最终检查时的视觉结果普遍良好，61.8%的人阅读6/12或更好。有不成比例的大量儿童的最终记录的敏锐度为
Background: Primary infantile glaucoma presents rarely, but can be responsible for significant visual morbidity. There is little information on the clinical features and visual outcome of a pure population of primary infantile glaucoma, as opposed to a mixed population of primary and secondary glaucoma or combined group of those with trabeculodysgenesis and iridotrabeculodysgenesis.Methods: We conducted a retrospective review of children with primary infantile glaucoma seen in south-eastern Australia between 1980 and 2000, using The Royal Children's Hospital ophthalmic diagnostic coding database.Results: Fifty-one patients with primary infantile glaucoma were identified (83 eyes). This equates to an estimated incidence of approximately 1 in 30 000 births. The mean +/- SD age at presentation was 135 +/- 84 days. 'Burnt-out' disease (megalocornea without raised intraocular pressure) was diagnosed in 10.8%. Goniotomy was the most commonly performed surgical procedure (69.4% of 72 eyes). Surgical success with one or two goniotomies was achieved in 74% of eyes. Visual outcomes at final review were generally good with 61.8% reading 6/12 or better. There were a disproportionately high number of children having a final recorded acuity of