Burden of depression in China, 1990-2017: Findings from the global burden of disease study 2017
Burden of depression in China, 1990-2017: Findings from the global burden of disease study 2017
复制标题
DOI：
10.1016/j.jad.2020.03.011
复制
发表时间：
2020-05-01
影响因子：
6.6
通讯作者：
Zhou, Maigeng
中科院分区：
文献类型：
--
作者：
Ren, Xinwen;Yu, Shicheng;Zhou, Maigeng
背景：抑郁症在中国已从1990年的第15位全因残疾调整生命年（DADs）上升到2017年的第10位。然而，抑郁症的负担和中国各省的流行趋势仍不清楚。本研究旨在估计中国不同性别、年龄、疾病类型和省级行政单位的抑郁症患病率和负担。方法：在2017年全球疾病负担研究（GBD）总体分析的基础上，分析1990 - 2017年中国抑郁症的年龄-性别和省份特异性患病率和抑郁症患病率。从1990年到2017年，每10万人中抑郁症的各年龄段患病率从3224.6（95% UI：2976.6-3509.1）至3990.5（95%UI：3667.8-4353.0），每10万人的DALY率从525.1（95%UI：373.5-719.0）上升到607.4（95%UI：427.7-820.2）。5-54岁人群患病率下降，55岁以上人群患病率上升。2017年女性患病率（5039.6，95%UI：4630.0-5502.8）明显高于男性（2984.9，95%UI：2736.0-3265.3）。所有省份的患病率和残疾调整生命年率均有所上升。结论：抑郁症已逐渐成为我国重要的公共卫生问题。政府应该立即采取措施防止抑郁症的发展。妇女和老年人患抑郁症的风险很高。
Background: Depression in China has risen from the 15th leading cause of all-cause disability-adjusted life years (DALYs) in 1990 to the 10th in 2017. However, the burden of depression and the epidemiological trend in Chinese provinces remain unclear. This study aimed to estimate the prevalence and burden of depression among different sexes, ages, disease types and provincial administrative units in China.Methods: Based on a general analysis of the Global Burden of Disease study (GBD) in 2017, we analyzed the age-sex- and province-specific prevalence and DALYs of depression in China from 1990 to 2017.Results: From 1990 to 2017, the all-age prevalence rate of depression per 100,000 rose from 3224.6 (95% UI:2976.6-3509.1) to 3990.5 (95% UI: 3667.8-4353.0), and the DALY rate per 100,000 rose from 525.1 (95% UI: 373.5-719.0) to 607.4 (95% UI: 427.7-820.2). The prevalence rate decreased in the population aged 5-54 years, and increased in the population aged over 55 years. In 2017, the prevalence rate of females (5039.6, 95% UI: 4630.0-5502.8) was significantly higher than that of males (2984.9, 95% UI: 2736.0-3265.3). The prevalence and DALY rate increased in all provinces. However, the age-standardized prevalence and DALYs rate decreased in 31 provinces.Conclusions: Depression has gradually become a major public health issue in China. The government should take measures to prevent the development of depression immediately. Women and the elderly are at high risk for depression.