Alginate-Polyethylene Oxide Blend Nanofibers and the Role of the Carrier Polymer in Electrospinning
Alginate-Polyethylene Oxide Blend Nanofibers and the Role of the Carrier Polymer in Electrospinning
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DOI：
10.1021/ie302385b
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发表时间：
2013-07-03
影响因子：
4.2
通讯作者：
Khan, Saad A.
中科院分区：
文献类型：
--
作者：
Saquing, Carl D.;Tang, Christina;Khan, Saad A.
我们在这里提出了一项系统的研究，以了解为什么海藻酸钠只能通过与另一种聚合物，特别是聚环氧乙烷(PEO)的混合物电纺成纤维。我们试图研究和理解PEO作为“载体聚合物”的作用。PEO的加入有利于降低藻酸盐溶液的电导率和表面张力，有助于纤维的形成。虽然PEO具有通过其醚基(-COC-)与金属阳离子(如海藻酸钠的钠离子)配位的能力，但在本研究中，我们使用PEO以及聚乙烯醇(PVA)证明了配位对可电纺性的影响很小。更重要的是，我们证明了PEO作为载体聚合物提供了静电纺丝所需的分子纠缠。由于所选择的载体聚合物提供了必要的缠结，这种载体聚合物必须是可电纺的、缠绕的并且具有高相对分子质量(PEO大于600 kDa)。在这些要求的基础上，我们规定在静电纺丝过程中，高相对分子质量缠绕的PEO的PEO-PEO相互作用是将藻酸盐从溶液带到纤维中的关键。此外，利用由此产生的对PEO作用的理解，我们能够通过使用更高分子量的PEO来增加藻酸盐浓度：使用2000 kDa PEO和添加Triton X-100表面活性剂，高达85wt%的藻酸盐，比以前报道的要高。
We present here a systematic investigation to understand why aqueous sodium alginate can only be electrospun into fibers through a blend with another polymer; specifically, polyethylene oxide (PEO). We seek to examine and understand the role of PEO as the "carrier polymer". The addition of PEO favorably reduces electrical conductivity and surface tension of the alginate solution, aiding in fiber formation. While PEO has the ability to coordinate through its ether group (-COC-) with metal cation like the sodium cation of sodium alginate, we demonstrate in this study using PEO as well as polyvinyl alcohol (PVA) that coordination may have little effect on electrospinnability. More importantly, we show that PEO as carrier polymer provides molecular entanglement that is required for electrospinning. Since the selected carrier polymer provides the necessary entanglement, this carrier polymer must be electrospinnable, entangled and of a high molecular weight (more than 600 kDa for PEO). On the basis of these requirements, we stipulate that the PEO-PEO interaction of the high molecular-weight entangled PEO is key to "carrying" the alginate from solution to fibers during electrospinning. Further, using the resulting understanding of the role of PEO, we were able to increase the alginate concentration by employing a higher molecular-weight PEO: up to 70 wt % alginate using 2000 kDa PEO and, with, the addition of Triton X-100 surfactant, up to 85 wt % alginate, higher than previously reported.