PERICYTES IN DIABETIC RETINOPATHY
PERICYTES IN DIABETIC RETINOPATHY
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DOI：
10.1136/bjo.50.3.134
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发表时间：
1966-01-01
影响因子：
4.1
通讯作者：
DEOLIVEIRA, F
中科院分区：
文献类型：
--
作者：
DEOLIVEIRA, F
最近，人们对壁内周细胞的作用给予了相当大的重视。在视网膜血管病理学中，其特异性损伤被认为在糖尿病视网膜病变的发生中具有重要意义。Cogan和他的同事（Cogan, Toussaint, and Kuwabara, 1961; Kuwabara and Cogan, 1963）提出了这些关于一个古老而困难的问题的令人振奋的新思想，值得仔细考虑。在目前的研究中，糖尿病视网膜病变的病理因此被重新检查，并考虑到他们的报告，以确定他们的结论可以支持到什么程度。本文不打算对有关内周细胞的大量有争议的文献进行综述；本文仅讨论其在糖尿病视网膜病变中的意义。
CONSIDERABLE significance has recently been attached to the role of intramural pericytes. inthe pathology of retinal vessels, and their specific injury is believed to have fundamental importance in the genesis of diabetic retinopathy. These stimulating new thoughts about an old and difficult problem have been advanced by Cogan and his co-workers (Cogan, Toussaint, and Kuwabara, 1961; Kuwabara and Cogan, 1963a) and merit careful consideration. In the present study the pathology of diabetic retinopathy has therefore been re-examined with their reports in mind, to determine how far their conclusions may be supported. No attempt will be made to review the large and controversial literaturedealing with intramural pericytes; this paper is concerned only with thesignificance of theiralteration in diabetic retinopathy.