Simple surface modification process to produce a transparent apatite-polystyrene composite for in situ observation of cell behavior
Simple surface modification process to produce a transparent apatite-polystyrene composite for in situ observation of cell behavior
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DOI：
10.1246/cl.2006.1300
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发表时间：
2006-11-05
影响因子：
1.6
通讯作者：
Ito, Atsuo
中科院分区：
文献类型：
--
作者：
Oyane, Ayako;Tsurushima, Hideo;Ito, Atsuo
采用简单的表面改性工艺在透明聚苯乙烯（PS）衬底上形成磷灰石层，其中磷灰石前体沉积在PS衬底表面，然后浸入相对磷灰石过饱和的磷酸钙溶液中。由此获得的磷灰石涂层的PS衬底具有高透明度，可以在透射光学显微镜下原位观察表面磷灰石层上的细胞行为。
An apatite layer was formed on a transparent polystyrene (PS) substrate using a simple surface modification process, in which apatite precursors were deposited on a PS substrate surface that was then immersed in a calcium phosphate solution supersaturated with respect to apatite. The apatite-coated PS substrate thus obtained was highly transparent, which enables in situ observation of cell behavior on the surface apatite layer under a transmission optical microscope.