Volumetric ellipsoid zone mapping for enhanced visualisation of outer retinal integrity with optical coherence tomography.
Volumetric ellipsoid zone mapping for enhanced visualisation of outer retinal integrity with optical coherence tomography.
复制标题
DOI：
10.1136/bjophthalmol-2015-307105
复制
发表时间：
2016-03
期刊：
影响因子：
--
通讯作者：
Ehlers JP
中科院分区：
文献类型：
--
作者：
Itoh Y;Vasanji A;Ehlers JP
光学相干断层扫描（OCT）的视网膜层完整性的客观评估目前是有限的。椭圆区（EZ）已被确定为OCT的一个重要特征，对黄斑病变具有重要的预后价值。在这份报告中，我们描述了一种新的评估工具，EZ完整性，提供视觉和定量评估的OCT数据集。利用该算法，我们描述了多个临床实例中的发现，包括正常对照、年龄相关性黄斑变性、药物作用（例如，ocriplasmin，羟氯喹），和手术操作的影响（例如，使用术中OCT进行膜剥离后）。EZ映射提供EZ完整性和EZ-视网膜色素上皮高度的正面可视化。此外，使用此评估工具进行体积、面积和线性测量也是可行的。
Objective assessment of retinal layer integrity with optical coherence tomography (OCT) is currently limited. The ellipsoid zone (EZ) has been identified as an important feature on OCT that has critical prognostic value in macular disorders. In this report, we describe a novel assessment tool for EZ integrity that provides visual and quantitative assessment across an OCT data set. Utilizing this algorithm, we describe the findings in multiple clinical examples, including normal controls, age-related macular degeneration, drug effects (e.g., ocriplasmin, hydroxychloroquine), and effects of surgical manipulation (e.g., following membrane peeling utilizing intraoperative OCT). EZ mapping provides both en face visualization of EZ integrity and EZ-retinal pigment epithelium height. Additionally, volumetric, area, and linear measurements are feasible using this assessment tool.