NOSOCOMIAL RESPIRATORY SYNCYTIAL VIRUS-INFECTIONS
NOSOCOMIAL RESPIRATORY SYNCYTIAL VIRUS-INFECTIONS
复制标题
DOI：
10.1056/nejm197512252932604
复制
发表时间：
1975-01-01
影响因子：
158.5
通讯作者：
MESSNER, MK
中科院分区：
文献类型：
--
作者：
BREESE, C;DOUGLAS, RG;MESSNER, MK
我们研究了社区爆发期间婴儿病房呼吸道合胞病毒感染的频率和严重程度。每隔三到四天，对所有婴儿和工作人员进行检查，并采集标本进行病毒分离。在两个月内，44名接触过病毒的婴儿中有14名感染了病毒。所有人都病了，四个人得了肺炎。感染组平均住院时间（21.5天）明显长于未感染组（9.2天，P < 0.001）。医院感染的风险可能与年龄或基础疾病无关，但与住院时间有关：住院一周或一周以上的婴儿中有45%受到感染，而且这一比例随着住院时间的延长而增加。24名工作人员中有10人也感染了病毒，似乎是病毒携带者。院内呼吸道合胞病毒感染是住院婴儿的主要风险，并增加了住院费用。（《新英格兰医学杂志》293：1343-1346，1975）
We studied the frequency and severity of respiratory syncytial virus infections acquired nosocomially on an infants' ward during a community outbreak. Every three or four days all infants and staff were examined, and specimens were obtained for viral isolation. During two months, 14 of 44 contact infants acquired the virus. All were ill, and four had pneumonia. Infected infants had a significantly longer mean hospital stay (21.5 days) than uninfected ones (9.2 days, P < 0.001). Risk of nosocomial infection could not be related to age or to underlying disease, but was linked to length of hospitalization: 45 per cent of infants hospitalized for one week or more became infected, and the percentage increased with length of stay. Ten of 24 staff members also acquired the virus and appeared to play a major role as virus carriers. Nosocomial respiratory syncytial virus infection poses a major risk for hospitalized infants and adds to hospital costs. (N Engl J Med 293:1343–1346, 1975)