An Overview and Update of Chronic Myeloid Leukemia for Primary Care Physicians.
An Overview and Update of Chronic Myeloid Leukemia for Primary Care Physicians.
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初级保健医生的慢性髓样白血病的概述和更新。
DOI：
10.4082/kjfm.2015.36.5.197
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发表时间：
2015-09
影响因子：
2.3
通讯作者：
Akhtari M
中科院分区：
文献类型：
--
作者：
Granatowicz A;Piatek CI;Moschiano E;El-Hemaidi I;Armitage JD;Akhtari M
慢性粒细胞白血病（CML）约占成人白血病的15%。40%的CML患者无症状，仅根据实验室异常检测出疾病。自2001年酪氨酸激酶抑制剂治疗以来，CML已成为大多数患者的慢性疾病。初级保健医生可能是第一个认识到CML新诊断的人。在已知的CML患者中，初级保健医生可能是第一个发现疾病进展或治疗不良反应的人。本文概述了慢性粒细胞白血病的临床表现、诊断方法和治疗注意事项。
Chronic myeloid leukemia (CML) accounts for approximately 15% of adult leukemias. Forty percent of patients with CML are asymptomatic, in whom the disease is detected solely based on laboratory abnormalities. Since the introduction of tyrosine kinase inhibitor therapy in 2001, CML has become a chronic disease for the majority of patients. Primary care physicians may be the first to recognize a new diagnosis of CML. In patients with known CML, the primary care physician may be the first to detect disease progression or adverse effects to therapy. This article provides an overview of the clinical presentation, diagnostic approach, and treatment considerations of CML.