CONTACT TRACING AND THE ESTIMATION OF SEXUAL MIXING PATTERNS - THE EPIDEMIOLOGY OF GONOCOCCAL INFECTIONS

CONTACT TRACING AND THE ESTIMATION OF SEXUAL MIXING PATTERNS - THE EPIDEMIOLOGY OF GONOCOCCAL INFECTIONS
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DOI:
10.1097/00007435-199307000-00001
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发表时间:
1993-07-01
影响因子:
3.1
通讯作者:
ANDERSON, RM
ANDERSON, RM
中科院分区:
医学4区
文献类型:
--
作者:
GARNETT, GP;ANDERSON, RM

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背景和目标:频繁更换性伴侣的核心群体的概念在性传播疾病(STD)流行病学研究中发挥了重要作用。人们普遍认为,核心组是重要的,在持续的感染,它提供了一个明智的目标,控制interventions.Goal的这项研究和研究设计:简单的数学模型被用来评估核心和非核心群体之间的性别混合的意义。从接触者追踪研究中公布的数据,其基础上的淋病发病率由居住区的核心组的定义,被用来获得估计的混合度内和组之间。结果:分析揭示了在城市研究地点的核心组内的高度混合模式,这表明,组内传播确保了淋球菌感染的持久性在整个社区。详细介绍了接触者追踪数据分析的扩展,以便于开发STD传播的数学模型。
Background and objectives: The concept of a core group of individuals who change sexual partners frequently has played an important role in the study of the epidemiology of sexually transmitted diseases (STDs). It is widely believed that the core group is important in the persistence of infection and that it provides a sensible target for control interventions.Goal of this study and study design: Simple mathematical models are used to assess the significance of sexual mixing between core and noncore groups. Published data from contact tracing studies, which base the definition of the core group on gonorrhea incidence by area of residence, are used to derive estimates of the degree of mixing within and between groups.Results: Analyses reveal patterns of high mixing within core groups in the urban study sites, which suggests that within-group transmission ensures the persistence of gonococcal infection in the community as a whole.Conclusions: An extension of the analysis of contact tracing data to facilitate the development of mathematical models of STD transmission is detailed.