The Nasal Cycle During Wakefulness and Sleep and Its Relation to Body Position
The Nasal Cycle During Wakefulness and Sleep and Its Relation to Body Position
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DOI：
10.1002/lary.24546
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发表时间：
2014-06-01
期刊：
影响因子：
2.6
通讯作者：
Kuehnel, Thomas S.
中科院分区：
文献类型：
--
作者：
Rohrmeier, Christian;Schittek, Silke;Kuehnel, Thomas S.
目的/假设：比较清醒和睡眠时鼻周期(NC)的发生、持续时间和相对幅度，并探讨NC与体位的关系。研究设计/方法：对20名健康受试者进行长期鼻流率测量，平均23.1小时清醒和睡眠。结果：50%的受试者在清醒状态下显示典型的NC，75%的受试者在睡眠时显示典型的NC。清醒周期为91.1分钟(+/-65.2；20-337)，睡眠周期显著增加至178分钟(+/-92.8；21-498)(P<；0.01)。清醒时工作时相对平均流量为67.6%(+/-8.0；58~90)，睡眠时显著高于睡眠时的82.0%(+/-6.8；63~93)(P<；0.01)。卧位时，体位与静息时相侧呈显著相关(r=0.67，P=0.024)。在很大程度上，位置变化导致随后的NC偏侧性改变(22%；P<；0.01)。相反，在很大程度上，位置移位先于NC偏侧改变(57.6%；P<；0.01)。仅有30.3%(P=0.16)的患者由于下鼻甲充血侧的反转而导致体位改变。结论：睡眠中NC的周期持续时间和波幅均大于清醒时的正常体力活动。睡眠期间身体位置的变化在很大程度上改变了NC在特定方向上的变化，但情况并非如此。
Objectives/Hypothesis: To compare the occurrence, duration, and relative amplitudes of the nasal cycle (NC) during wakefulness and sleep, and to investigate the relationship of the NC to body position.Study Design/Methods: In 20 healthy subjects, the NC was measured by long-term rhinoflowmetry for an average 23.1 hours during wakefulness and sleep. Head and body position were also recorded during the night.Results: A classic NC was displayed by 50% of subjects during wakefulness and by 75% of the subjects during sleep. Cycle duration during wakefulness was 91.1 minutes (+/- 65.2; 20-337), increasing significantly during sleep to 178 minutes (+/- 92.8; 21-498) (P < 0.01). The relative mean flow of the working phase during wakefulness was 67.6% (+/- 8.0; 58-90), and it was significantly higher during sleep at 82.0% (+/- 6.8; 63-93) (P < 0.01). On recumbency, there was a significant correlation between body position and resting phase side (r=0.67; P=0.024). To a significant extent, positional shifts led to subsequent NC laterality changes (22%; P < 0.01). Conversely, to a significant extent, positional shifts preceded NC laterality changes (57.6%; P < 0.01). Body position changed in a nonsignificant number of cases (30.3%; P=0.16) due to reversal of the congestion side of the inferior turbinates.Conclusion: The results of our study show that the NC during sleep is characterized by longer cycle durations and greater amplitudes than during wakefulness on normal physical activity. Shifts in body position during sleep alter the NC in a specific direction to a significant extent, but the opposite is not the case.