INTRACEREBRAL TEMPERATURES IN FREE-MOVING CATS
INTRACEREBRAL TEMPERATURES IN FREE-MOVING CATS
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DOI：
10.1152/ajplegacy.1966.211.3.755
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发表时间：
1966-01-01
影响因子：
--
通讯作者：
HANAI, T
中科院分区：
文献类型：
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作者：
DELGADO, JMR;HANAI, T
在自由活动的猫身上，通过永久植入的热电偶记录了脑电活动和大脑温度。结果表明：大脑是热异质性的，比血液具有更大的不稳定性，杏仁核-梨状区比下丘脑表现出更大的反应性。自发的运动活动或通过磁带录制的声音来提醒猫，会在大脑中产生适度的热增加。含有情绪内容的刺激效果更大。在以慢波活动为特征的睡眠期间，大脑温度下降。矛盾的睡眠伴随着缓慢的体温上升。抚摸是提高脑内温度最有效的刺激之一，主要影响梨形区，而血液温度保持不变。饮用冷饮对颈动脉温度的降低比对大脑温度的降低更大。加热猫的头部，运动皮层的温度比眼眶皮层或直肠的温度要高得多。腹腔注射乙酰胆碱和氯丙嗪使体温下降，而肾上腺素则使脑内温度升高。在运动阈值处对大脑进行电刺激并没有改变大脑温度。杏仁核刺激引起的癫痫发作伴随着杏仁核和运动皮层比丘脑和下丘脑更大的热上升和颈动脉内温度下降。与运动皮层和下丘脑相比，丘脑癫痫发作使丘脑网状结构的温度升高更大。在电诱发癫痫发作期间，动物的Curarization降低了脑内温度的升高。
In free-moving cats, electrical activity and temperature of the brain were recorded by means of permanently implanted thermocouples. Results were as follows: The brain is thermaUy heterogeneous and has greater lability than the blood with the amygdala-pyriform region showing greater reactivity than the hypothalamus. Spontaneous motor activity or alerting of the cat by tape-recorded sounds produced a moderate thermal increase in the brain. Stimuli with emotional content had a greater effect. During sleep characterized by slow-ave activity, brain temperature decreased. Paradoxical sleep was accompanied by a slow thermal rise. Petting was one of the most effective stimuli for increasing intracerebral temperature affecting mainly the pyrtform region whereas blood temperature remained constant. Ingestion of cold drinks produced a greater decrease in carotid than in cerebral temperature. Heating the cat''s head augmented temperature in the motor cortex far more than in the orbital cortex or rectum. Intraperitoneal acetylchollne and chlorpromazine produced a drop whereas adrenaline Induced a rise in intracerebral temperature. Electrical stimulation of the brain at motor threshold did not modify cerebral temperature. Seizures evoked by amygdala stimulation were accompanied by greater thermal rise in amygdala and motor cortex than in thalamus and hypothalamus and by a fall in the intracarotid temperature. Thalamlc seizures produced a greater increase in temperature in thalamuand reticular formation than in motor cortex and hypothalamus. Curarization of the animal diminished the increase of intracerebral temperature during electrically evoked seizures.