The long-term influence of biotin supplementation on hoof horn quality in horses.
The long-term influence of biotin supplementation on hoof horn quality in horses.
复制标题
补充生物素对马蹄角质量的长期影响。
DOI：
10.5167/uzh-113156
复制
发表时间：
1994
影响因子：
0.7
通讯作者：
J. Schulze
中科院分区：
文献类型：
--
作者：
H. Geyer;J. Schulze
在一项为期1至6年的长期研究中，研究了膳食生物素对蹄角脆性和蹄片断裂的马的影响。97匹马每100至150公斤体重每天服用5毫克生物素；11匹马不补充生物素，作为对照。每三至四个月对所有马的蹄子进行宏观评估。分别对25匹马和15匹马的近壁蹄角标本进行了组织学和物理检查。正常冠状动脉角抗拉强度≥60 N/mm2；在组织学改变的区域减少，最低值为20 N/mm2。通过宏观和组织学检查，补充生物素的马的蹄角状况在补充8至15个月后得到改善。在整个研究过程中，大多数对照马的蹄角状况保持不变。添加生物素的马与对照组的冠状角生长速率相同。在减少或停止补充生物素后，10匹马中有7匹的蹄角状况恶化。结果表明，严重蹄角病变的马应持续补充足量生物素。
The influence of dietary biotin in horses with brittle hoof horn and chipped hooves was investigated in a long-term study, which was performed over a period from one to six years. 97 horses received 5 mg of biotin per 100 to 150 kg of body weight, per os, daily; 11 horses were not supplemented with biotin and served as controls. The hooves of all horses were evaluated macroscopically every three to four months. Hoof horn specimens of the proximal wall were examined histologically and physically in 25 and 15 horses, respectively. The tensile strength of normal coronary horn was 60 N/mm2 or greater; it was reduced in areas of histological alterations, the lowest value being 20 N/mm2. The hoof horn condition of the biotin-supplemented horses improved after eight to 15 months of supplementation as determined by macroscopic and histologic examinations. The hoof horn condition of most control horses remained constant throughout the study. The growth rate of the coronary horn of horses supplemented with biotin and of control horses was the same. The hoof horn condition deteriorated in 7 of 10 horses after biotin supplementation was reduced or terminated. It was concluded that biotin should be continuously supplemented at the full dosage in horses with severe hoof horn alterations.