The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults
The relationship between green tea and total caffeine intake and risk for self-reported type 2 diabetes among Japanese adults
复制标题
DOI：
10.7326/0003-4819-144-8-200604180-00005
复制
发表时间：
2006-04-18
影响因子：
39.2
通讯作者：
Tamakoshi, A
中科院分区：
文献类型：
--
作者：
Iso, H;Date, C;Tamakoshi, A
背景：在西方人群中，喝咖啡可以降低患2型糖尿病的风险；然而，绿茶、红茶和乌龙茶的效果尚不清楚。目的：探讨这些饮料的消费与糖尿病风险之间的关系。设计：回顾性队列研究。背景：日本25个社区。参与者：共17 413人（6727名男性和10 686名女性，占原始研究人群的49%），年龄在40至65岁之间；基线生活方式调查时无2型糖尿病、心血管疾病或癌症病史；并完成5年随访问卷。调查对象和非调查对象的基线体重指数水平没有差异。测量方法：咖啡消费问卷；红茶、绿茶和乌龙茶；还有医生诊断的糖尿病。结果：在5年随访期间，有231名男性和213名女性自报新发糖尿病病例444例（5年发病率分别为3.4%和2.0%）。在调整了年龄、性别、体重指数和其他风险因素后，绿茶和咖啡的摄入量与患糖尿病的风险呈负相关。经常喝绿茶和咖啡（每天6杯绿茶和每天3杯咖啡）的参与者患糖尿病的多变量优势比分别为0.67 （95% Cl， 0.47至0.94）和0.58 (Cl， 0.37至0.90)，与那些每周喝不到一杯的参与者相比。没有发现饮用红茶或乌龙茶与患糖尿病风险之间的联系。从这些饮料中摄入的总咖啡因与糖尿病风险降低33%有关。这种反向关联在女性和超重男性中更为明显。局限性：糖尿病是自我报告的，没有关于苏打水消费的数据，随访率低。结论：饮用绿茶、咖啡和总咖啡因与降低2型糖尿病的风险有关。
Background: in western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear.Objective: To examine the relationship between consumption of these beverages and risk for diabetes.Design: Retrospective cohort study.Setting: 25 communities across Japan.Participants: A total of 17 413 persons (6727 men and 10 686 women; 49% of the original study population) who were 40 to 65 years of age; had no history of type 2 diabetes, cardiovascular disease, or cancer at the baseline lifestyle survey; and completed the 5-year follow-up questionnaire. There was no difference in body mass index levels at baseline between respondents and non-respondents.Measurements: Questionnaire on consumption of coffee; black, green, and oolong teas; and physician-diagnosed diabetes. Results: During the 5-year follow-up, there were 444 self-reported new cases of diabetes in 231 men and 213 women (5-year event rates, 3.4% and 2.0%, respectively). Consumption of green tea and coffee was inversely associated with risk for diabetes after adjustment for age, sex, body mass index, and other risk factors. Multivariable odds ratios for diabetes among participants who frequently drank green tea and coffee ( :6 cups of green tea per day and 3 cups of coffee per day) were 0.67 (95% Cl, 0.47 to 0.94) and 0.58 (Cl, 0.37 to 0.90), respectively, compared with those who drank less than I cup per week. No association was found between consumption of black or oolong teas and the risk for diabetes. Total caffeine intake from these beverages was associated with a 33% reduced risk for diabetes. These inverse associations were more pronounced in women and in overweight men.Limitations: Diabetes was self-reported, no data were available on consumption of soda, and the follow-up rate was low.Conclusions: Consumption of green tea, coffee, and total caffeine was associated with a reduced risk for type 2 diabetes.