Termination patterns of complex partial seizures: An intracranial EEG study.
Termination patterns of complex partial seizures: An intracranial EEG study.
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DOI：
10.1016/j.seizure.2015.08.004
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发表时间：
2015-11
期刊：
影响因子：
--
通讯作者：
Bergey GK
中科院分区：
文献类型：
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作者：
Afra P;Jouny CC;Bergey GK
虽然癫痫发作模式已被许多报告的主题，有几个癫痫发作终止的研究。在这项研究中，我们报告了颅内阵列记录的部分性癫痫发作的同步和异步终止模式的发生率。数据收集自接受颅内电极术前评估的难治性复杂部分性癫痫发作患者。起源于内侧颞叶和新皮质区域的癫痫发作患者根据癫痫发作终止模式分为三组：仅同步（So），仅异步（Ao）或混合（S/A，同步和异步终止模式）。MT组中88%的患者癫痫发作具有完全终止（38%）或混合终止（50%）的同步模式。82%的NC组有同步终止模式的癫痫发作（52%）或混合（30%）。在NC组中，So和Ao组之间的癫痫发作持续时间范围存在显著差异，Ao表现出更高的变异性。两组中同步终止的癫痫发作变异性较低。同步性癫痫发作终止是颞叶内侧或新皮质发作的复杂部分性癫痫发作的常见模式。这可能反映了癫痫病灶处的刻板网络行为或动态。
While seizure onset patterns have been the subject of many reports, there have been few studies of seizure termination. In this study we report the incidence of synchronous and asynchronous termination patterns of partial seizures recorded with intracranial arrays. Data were collected from patients with intractable complex partial seizures undergoing presurgical evaluations with intracranial electrodes. Patients with seizures originating from mesial temporal and neocortical regions were grouped into three groups based on patterns of seizure termination: synchronous only (So), asynchronous only (Ao), or mixed (S/A, with both synchronous and asynchronous termination patterns). 88% of the patients in the MT group had seizures with a synchronous pattern of termination exclusively (38%) or mixed (50%). 82% of the NC group had seizures with synchronous pattern of termination exclusively (52%) or mixed (30%). In the NC group, there was a significant difference of the range of seizure durations between So and Ao groups, with Ao exhibiting higher variability. Seizures with synchronous termination had low variability in both groups. Synchronous seizure termination is a common pattern for complex partial seizures of both mesial temporal or neocortical onset. This may reflect stereotyped network behavior or dynamics at the seizure focus.