OBSERVATIONS ON FOETAL GROWTH IN MULTIPLE PREGNANCY IN MAN
OBSERVATIONS ON FOETAL GROWTH IN MULTIPLE PREGNANCY IN MAN
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DOI：
10.1677/joe.0.0080386
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发表时间：
1952-01-01
影响因子：
4
通讯作者：
RECORD, RG
中科院分区：
文献类型：
--
作者：
MCKEOWN, T;RECORD, RG
数据以出生体重表示。1947年在英国伯明翰出生的17，072例单胎和253对双胞胎，在英国较大的妇产医院出生的218对三胞胎，以及1931-1951年在英国出生的24对四胞胎的妊娠期和持续时间。单胎、双胎、三胎和四胎的平均体重。分别为7.43、5.27、4.00和3.07磅，平均妊娠期分别为280.5、261.6、246.8和2368天。平均胎儿重量似乎是独立的窝仔数，直到约27周的妊娠。多胎胎儿的生长速度比单胎胎儿慢，从妊娠阶段开始，随窝仔数变化如下：四胎从约26周开始，三胎从27周开始，双胎从30周开始。在这些妊娠意味着窝。接近。一样的为以下观点提供了支持：大窝仔中胎儿生长迟缓至少部分归因于子宫拥挤，拥挤子宫中胎儿生长受限可能由胎盘平均窝仔重量施加。单胎、双胎、三胎和四胎的出生体重分别为7.43、10.53、12.00和12.28磅。这些观察结果与多胎妊娠早临产是由于子宫扩张的观点并不矛盾，如果我们假设amt。在妊娠的最后几周，子宫所能忍受的膨胀程度随着妊娠的进展而降低。
Data are presented on birth wt. and duration of gestation of 17,072 singletons and 253 pairs of twins born in Birmingham (England) in 1947, 218 sets of triplets born in the larger maternity hospitals of Great Britain, and 24 sets of quadruplets born in Great Britain in 1931-1951. Singletons, twins, triplets and quadruplets had mean wts. of 7.43, 5.27, 4.00, and 3.07 lbs., and mean durations of gestation of 280.5, 261.6, 246.8, and 2368 days, respectively. Mean fetal wt. appears to be independent of litter size until about the 27th week of gestation. The rate of growth of multiple fetuses is slower than that of single fetuses from a stage of gestation which varies with size of litter as follows: quadruplets from about 26 weeks, triplets from 27 weeks, and twins from 30 weeks. At these gestations mean litter wts. are approx. the same. Support is provided for the view that retardation of fetal growth in large litters is attributable at least in part to crowding in the uterus and that the restriction on fetal growth in the crowded uterus may be imposed by the placenta Mean litter wts. of singletons, twins, triplets, and quadruplets at birth are, respectively, 7.43, 10.53, 12.00, and 12.28 lbs. These observations are not inconsistent with the view that the early onset of labor in multiple pregnancy is due to distension of the uterus, if we suppose that the amt. of distension which the uterus will tolerate during the last weeks of gestation decreases as pregnancy advances.