Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.

Impact of Intrapartum Oral Azithromycin on the Acquired Macrolide Resistome of Infants' Nasopharynx: A Randomized Controlled Trial.
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DOI:
10.1093/cid/ciaa609
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发表时间:
2020-12-15
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
--
通讯作者:
Roca A
Roca A
中科院分区:
其他
文献类型:
--
作者:
Bojang A;Baines SL;Camara B;Guerillot R;Donovan L;Marqués RS;Secka O;D'Alessandro U;Bottomley C;Howden BP;Roca A

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In a post hoc analysis of samples from an intrapartum azithromycin randomized clinical trial, we found that children whose mothers had been treated with the drug had higher prevalence of macrolide-resistance genes msr(A) and ermC at 28 days but not at 12 months. The 2 genes were positively associated in the nasopharynx. NCT1800942.
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