Stage I squamous cell carcinoma of vagina complicating pregnancy: Successful conservative treatment
Stage I squamous cell carcinoma of vagina complicating pregnancy: Successful conservative treatment
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DOI：
10.1016/j.ygyno.2005.05.007
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发表时间：
2005-09-01
影响因子：
4.7
通讯作者：
Tanaka, K
中科院分区：
文献类型：
--
作者：
Fujita, K;Aoki, Y;Tanaka, K
背景妊娠期阴道鳞状细胞癌是非常罕见的情况。患者为33岁女性，妊娠23周时主诉阴道褐色分泌物。在当时的盆腔检查中，在阴道后穹窿处发现了一个2 × 2 cm的肿块。病理切片证实为非角化型浸润性鳞状细胞癌。她希望继续妊娠，并将治疗推迟到分娩后。在妊娠23周时，我们进行了广泛的局部切除，确认T1期。在妊娠33周时，在剖宫产时进行盆腔淋巴结切除术，以确保病理学上的淋巴结状态。此外，她开始在辅助设置通过阴道圆柱腔内近距离放射治疗。她是36个月，从她的初次手术，并保持无病。结论。对于妊娠合并原发性I期阴道鳞状细胞癌患者，治疗应个体化。(c)2005年爱思唯尔公司All rights reserved.
Background. Vaginal squamous cell carcinoma in pregnancy is very rare situation.Case. The patient was a 33-year-old woman, presenting with a complaint of vaginal brownish discharge at a 23 weeks of gestation. On pelvic examination at that time, a 2 by 2 cm mass on posterior vaginal fornix was seen. Biopsy of the lesion demonstrated a nonkeratinizing type invasive squamous cell carcinoma. She desired to continue the pregnancy and postpone the treatment until after delivery. On 23 weeks of gestation, we performed wide local excision, confirming T1 stage. On 33 weeks of gestation, a pelvic lymphadenectomy was carried out at the time of cesarean section to secure lymph node status pathologically. Further, she began intracavitary brachytherapy via vaginal cylinder in an adjuvant setting. She is 36 months from her initial surgery and remains disease free.Conclusion. Treatment could be individualized for primary stage I vaginal squamous cell carcinoma complicating pregnancy. (c) 2005 Elsevier Inc. All rights reserved.