RELATION BETWEEN MEMBRANE POTENTIAL CHANGES + TENSION IN BARNACLE MUSCLE FIBERS
RELATION BETWEEN MEMBRANE POTENTIAL CHANGES + TENSION IN BARNACLE MUSCLE FIBERS
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DOI：
10.1085/jgp.48.2.225
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发表时间：
1964-01-01
影响因子：
3.8
通讯作者：
HAGIWARA, S
中科院分区：
文献类型：
--
作者：
EDWARDS, C;CHICHIBU, S;HAGIWARA, S
用轴向金属电极对藤壶（Balanus nubilus达尔文）的单根肌纤维施加恒流脉冲。用类似的电极测量发生在大部分肌纤维上的膜电位变化。去极化脉冲，如果电压大于阈值，产生张力。张力的大小是去极化脉冲的大小和持续时间的函数。去极化和紧张发作之间的潜伏期只能部分归因于机械因素。AC刺激产生张力，但达到张力的稳态水平需要5至10秒。肌肉在高钾下去极化，并在挛缩终止后进行研究。如果不太去极化，进一步去极化产生张力。终止超极化脉冲也会产生张力，而张力衰减得相当缓慢。超极化脉冲减少或消除了任何预先存在的紧张。因此，似乎在膜电位的某些值处建立了张力，但也存在缓慢的调节过程。
Constant current pulses have been applied to single muscle fibers of the barnacle, Balanus nubilus Darwin, with an axial metal electrode. The membrane potential change, which took place over a large part of the muscle fiber, was measured with a similar electrode. Depolarizing pulses, if the voltage was greater than threshold, produced tension. The size of the tension was a function of the magnitude and the duration of the depolarizing pulses. The latency between the onset of depolarization and tension can be only in part attributable to mechanical factors. AC stimulation produced tension, but 5 to 10 seconds were required for the steady-state level of the tension to be reached. Muscles were depolarized in elevated K and studied after the contracture had terminated. If not too depolarized, further depolarization produced tension. Termination of hyperpolarizing pulses also produced tension, which decayed quite slowly. Hyperpolarizing pulses reduced, or abolished, any preexisting tension. Thus, it appears that at certain values of the membrane potential tension is set up, but there is also a slow process of accommodation present.