Study of blood flow in several benchmark micro-channels using a two-fluid approach.
Study of blood flow in several benchmark micro-channels using a two-fluid approach.
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DOI：
10.1016/j.ijengsci.2015.06.004
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发表时间：
2015-10-01
影响因子：
6.6
通讯作者：
Massoudi M
中科院分区：
文献类型：
--
作者：
Wu WT;Yang F;Antaki JF;Aubry N;Massoudi M
已知在其特征尺寸（例如，其直径）在20至500微米的范围内，血液表现为非牛顿流体，表现出复杂的现象，例如剪切稀化、应力松弛，以及多组分行为，例如Fahraeus效应、血浆撇除等。为了描述血液的这些非牛顿和多组分特性，使用混合物理论的框架，应用双流体模型，其中将血浆作为牛顿流体处理，将红细胞（RBC）作为剪切稀化流体处理。使用OpenFOAM®实现了包含本构模型的计算流体动力学（CFD）模拟，其中对包括突然膨胀和各种驱动槽和裂缝的基准问题进行了数值研究。数值计算结果与实验结果吻合较好，无论是速度场和红细胞的体积分数分布。
It is known that in a vessel whose characteristic dimension (e.g., its diameter) is in the range of 20 to 500 microns, blood behaves as a non-Newtonian fluid, exhibiting complex phenomena, such as shear-thinning, stress relaxation, and also multi-component behaviors, such as the Fahraeus effect, plasma-skimming, etc. For describing these non-Newtonian and multi-component characteristics of blood, using the framework of mixture theory, a two-fluid model is applied, where the plasma is treated as a Newtonian fluid and the red blood cells (RBCs) are treated as shear-thinning fluid. A computational fluid dynamic (CFD) simulation incorporating the constitutive model was implemented using OpenFOAM® in which benchmark problems including a sudden expansion and various driven slots and crevices were studied numerically. The numerical results exhibited good agreement with the experimental observations with respect to both the velocity field and the volume fraction distribution of RBCs.