An Ultra-Brief Screening Scale for Anxiety and Depression: The PHQ-4
An Ultra-Brief Screening Scale for Anxiety and Depression: The PHQ-4
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DOI：
10.1176/appi.psy.50.6.613
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发表时间：
2009-11-01
期刊：
影响因子：
3.4
通讯作者：
Loewe, Bernd
中科院分区：
文献类型：
--
作者：
Kroenke, Kurt;Spitzer, Robert L.;Loewe, Bernd
背景：在门诊和一般人群中最常见的精神障碍是抑郁和焦虑，它们经常共存。这两种疾病都与相当大的残疾有关。目的：当疾病同时发生时，残疾更大。作者试图为这两种疾病测试一种超简短的筛查工具。方法：采用经验证的抑郁和焦虑两项超简短筛选问卷，组成《患者抑郁和焦虑健康问卷》（PHQ-4）。研究人员分析了来自美国15家初级保健诊所的2149名患者的数据。结果：因子分析证实了两个离散因素（抑郁和焦虑）解释了84%的总方差。PHQ-4评分的增加与功能损害、残疾天数和医疗保健使用密切相关。焦虑对独立于抑郁的功能状态有实质性影响。结论：PHQ-4是一种有效的超简短的检测焦虑和抑郁障碍的工具。（心身病学2009；50:613-621）
Background: The most common mental disorders in both outpatient settings and the general population are depression and anxiety, which frequently coexist. Both of these disorders are associated with considerable disability. Objective: When the disorders co-occur, the disability is even greater. Authors sought to test an ultra-brief screening tool for both. Method: Validated two-item ultra-brief screeners for depression and anxiety were combined to constitute the Patient Health Questionnaire for Depression and Anxiety (the PHQ-4). Data were analyzed from 2,149 patients drawn from 15 primary-care clinics in the United States. Results: Factor analysis confirmed two discrete factors (Depression and Anxiety) that explained 84% of the total variance. Increasing PHQ-4 scores were strongly associated with functional impairment, disability days, and healthcare use. Anxiety had a substantial effect on functional status that was independent of depression. Conclusion: The PHQ-4 is a valid ultra-brief tool for detecting both anxiety and depressive disorders. (Psychosomatics 2009; 50: 613-621)