The sequences of an expressed rat α-tubulin gene and a pseudogene with an inserted repetitive element
The sequences of an expressed rat α-tubulin gene and a pseudogene with an inserted repetitive element
复制标题
表达的大鼠α-微管蛋白基因和具有重复元件的假基因的插入序列
作者：
I. Lemischka;P. Sharp
大鼠基因组包含与大鼠α-微管蛋白mRNA密切相关的两个片段。两者都已被克隆，并提供了完整的核苷酸序列。对其中一个的结构和序列的分析确定它是一个功能性α-微管蛋白基因。第二个片段是加工的α-微管蛋白假基因。将该假基因与mRNA和编码α-微管蛋白的基因进行比较，强烈表明成熟的mRNA参与了其起源。假基因和一个分散的重复元件插入其中的功能可能反映了一个共同的RNA介导的插入过程。
The rat genome contains two segments closely related to a rat α-tubulin mRNA. Both have been cloned and complete nucleotide sequences are presented. Analysis of the structure and sequence of one of these establishes it as a functional α-tubulin gene. The second segment is a processed α-tubulin pseudogene. Comparison of this pseudogene to the mRNA and gene coding for α-tubulin strongly suggests that a mature mRNA was involved in its origin. Features of the pseudogene and a dispersed repetitive element inserted within it possibly reflect a common RNA-mediated process of insertion.
DOI：
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发表时间：
1982
期刊：
The Journal of biological chemistry
影响因子：
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作者：
Li,WY;Reddy,R;Henning,D;Epstein,P;Busch,H
通讯作者：
Busch,H