Prevalence of age-related lens opacities in a population. The Beaver Dam Eye Study.
Prevalence of age-related lens opacities in a population. The Beaver Dam Eye Study.
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DOI：
10.1016/s0161-6420(92)31934-7
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发表时间：
1992-04
期刊：
影响因子：
13.7
通讯作者：
B. Klein;R. Klein;K. L. Linton
中科院分区：
文献类型：
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作者：
B. Klein;R. Klein;K. L. Linton
晶状体相关的透镜混浊是常见的，并且是视力丧失的常见原因。比弗坝眼科研究旨在评估美国农村社区透镜混浊的患病率和严重程度。通过私人人口普查确定的43至84岁的成年人接受了检查并参加了研究（n = 4926）。拍摄镜片照片，并根据标准化方案以设盲方式进行分级。对于核硬化，更严重的水平更常见于老年组和女性。总体而言，17.3%的核硬化严重程度超过5级严重程度量表中的3级。皮质混浊随着年龄的增长而增加，在女性中更常见。他们被发现在16.3%的人口。6.0%的人群发生后囊下混浊。有一个明显的趋势，即在老年人中流行率更高，但没有性别影响。在65 - 74岁年龄组中，早期白内障的发生率在两性中均有所增加，但在75岁及以上年龄组中则有所下降。迟发性白内障的发生率随年龄增长而增加。妇女比男子受到的影响更严重。本研究证实，透镜混浊在美国成人中很常见。这些数据对于满足社会和保健需求十分重要。重要的是要确定白内障的原因，以制定预防计划。
Age-related lens opacities are common and are a frequent cause of loss of vision. The Beaver Dam Eye Study was designed to estimate the prevalence and severity of lens opacities in a rural community in the United States. Adults between the ages of 43 and 84 years, identified by private census, were examined and participated in the study (n = 4926). Photographs were taken of the lenses and were graded in masked fashion according to a standardized protocol. For nuclear sclerosis, more severe levels occurred more commonly in older age groups and in women. Overall, 17.3% had nuclear sclerosis more severe than level 3 in a 5-step scale of severity. Cortical opacities increased with increasing age and were more common in women. They were found in 16.3% of the population. Posterior subcapsular opacities occur in 6.0% of the population. There was a significant trend of greater prevalence at older ages, but no sex effect. The frequency of early cataract increased in both sexes through the age group 65 to 74 years, but declined in those 75 years of age and older. The frequency of late cataract increased consistently with age. Women were more severely affected than men. This study confirms that lens opacities are common in adults in the United States. These data are important for providing for social and health care needs. It is important to determine causes of cataracts in order to develop preventive programs.