MAGNETIZATION TRANSFER CONTRAST IN MR IMAGING OF THE HEART
MAGNETIZATION TRANSFER CONTRAST IN MR IMAGING OF THE HEART
复制标题
DOI：
10.1148/radiology.180.3.1871277
复制
发表时间：
1991-09-01
期刊：
影响因子：
19.7
通讯作者：
HEINEMAN, FW
中科院分区：
文献类型：
--
作者：
BALABAN, RS;CHESNICK, S;HEINEMAN, FW
对磁化传递对比 (MTC) 在短回波时间 (TE) 心脏磁共振 (MR) 成像中的使用进行了评估。 对于大多数心脏 MR 成像方案，长 TE 和短重复时间或外源性血管内药物用于在心室壁和腔之间产生对比度以及检测心室壁的病理状况。 长 TE 图像的主要问题是心脏的运动降低了 TE 期间图像的空间分辨率。 然而，MTC 是由脉冲间延迟期间的偏共振辐射产生的，对运动伪影相对不敏感。 使用短 TE（5-15 毫秒）梯度回忆回波序列对有或没有 MTC 的心脏进行成像。 这些研究表明，MTC 可用于极大地改善短 TE 图像中心肌壁和血室之间的对比度，并可能为病理心肌的组织表征提供有用的参数。
The use of magnetization transfer contrast (MTC) in short-echo-time (TE) cardiac magnetic resonance (MR) imaging was evaluated. For most cardiac MR imaging protocols, either long TE and short repetition time or exogenous intravascular agents are used for generating contrast between the ventricular wall and cavity as well as detecting pathologic conditions of the ventricular wall. The major problem with long-TE images is that the motion of the heart degrades the spatial resolution of the image during the TE period. However, MTC is generated by an off-resonance irradiation during the interpulse delay period that is relatively insensitive to motion artifacts. Short-TE (5-15 msec) gradient-recalled echo sequences were used for imaging the heart with and without MTC. These studies revealed that MTC can be used to greatly improve the contrast between the myocardial wall and blood chamber in short-TE images and may provide useful parameters for tissue characterization in pathologic cardiac muscle.