Communication challenges for nongeneticist physicians relaying clinical genomic results
Communication challenges for nongeneticist physicians relaying clinical genomic results
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DOI：
10.2217/pme-2017-0008
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发表时间：
2017-09-01
影响因子：
2.3
通讯作者：
Ubel, Peter A.
中科院分区：
文献类型：
--
作者：
Arora, Nonie S.;Davis, J. Kelly;Ubel, Peter A.
目的：确定在临床环境中使用基因组测序（GS）的行为挑战。材料和方法：我们观察了普通内科医生和非遗传专家如何向MedSeq项目注册的患者提供GS结果。利用这种披露互动的记录，我们对沟通行为进行了定性观察，这些行为可能会限制GS结果的有用性，直到达到主题饱和点。结果：研究结果包括基因组术语的混淆，信息数量或复杂性的困难，以及向患者传达复杂风险信息的困难。我们观察到，一些医生普遍轻视GS的临床价值，有时在健康行为改变方面沟通无效。结论：克服这些行为挑战是充分利用临床GS结果的必要条件。
Aim: Identify the behavioral challenges to the use of genome sequencing (GS) in a clinical setting. Materials & methods: We observed how general internists and nongenetic specialists delivered GS results to patients enrolled in the MedSeq Project. Using transcripts of such disclosure interactions, we made qualitative observations of communication behaviors that could limit the usefulness of GS results until reaching the point of thematic saturation. Results: Findings included confusion regarding genomic terminology, difficulty with the volume or complexity of information and difficulties communicating complex risk information to patients. We observed a broad dismissal of clinical value of GS by some physicians and sometimes ineffective communication regarding health behavior change. Conclusion: Overcoming these behavioral challenges is necessary to make full use of clinical GS results.