Gain-loss asymmetry in neural correlates of temporal discounting: An approach-avoidance motivation perspective.
Gain-loss asymmetry in neural correlates of temporal discounting: An approach-avoidance motivation perspective.
复制标题
时间贴现神经关联中的增益-损失不对称：接近-回避动机视角
DOI：
10.1038/srep31902
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发表时间：
2016-08-25
影响因子：
4.6
通讯作者：
Liang ZY
中科院分区：
文献类型：
--
作者：
Zhang YY;Xu L;Rao LL;Zhou L;Zhou Y;Jiang T;Li S;Liang ZY
时间贴现中的损益不对称（即，当个人对收益的折扣大于损失时）与许多问题和成瘾行为有关，导致巨大的个人和社会成本。根据先前的研究结果，我们推测，趋避动机会调节得失不对称。为了验证这一推测，我们通过分析功能连接来研究动机对得失不对称的影响。我们发现，接近和回避动机与内侧眶额皮层（MOFC）和背外侧前额叶皮层之间的功能连接和MOFC和后顶叶皮层（PPC）之间的功能连接在增益域呈负相关。只有回避动机被发现与内侧前额叶皮层（MPFC）和后扣带皮层（PCC）之间的功能连接以及MPFC和损失域中的前扣带皮层之间的功能连接呈正相关。我们的研究结果表明，接近-回避动机和神经相关的关系产生了一个不对称的模式之间的收益和损失域的时间折扣。因此，我们提供了新的见解来理解损益不对称的时间折扣。
Gain-loss asymmetry in temporal discounting (i.e., when individuals discount gains more than losses) has been implicated in numerous problematic and addictive behaviors, resulting in enormous personal and societal costs. On the basis of findings from a previous study, we speculated that approach-avoidance motivation would modulate gain-loss asymmetry. To test this speculation, we examined the effects of motivation on gain-loss asymmetry by analyzing functional connectivity. We found that approach and avoidance motivation were negatively associated with functional connectivity between the medial orbitofrontal cortex (MOFC) and the dorsolateral prefrontal cortex and functional connectivity between the MOFC and the posterior parietal cortex (PPC) in the gain domain. Only avoidance motivation was found to be positively associated with functional connectivity between the medial prefrontal cortex (MPFC) and the posterior cingulate cortex (PCC) as well as between the MPFC and the insula in the loss domain. Our findings suggest that the relationships of approach-avoidance motivation and neural correlates yielded an asymmetrical pattern between the gain and loss domains in temporal discounting. Thus, we provide new insight into understanding gain-loss asymmetry in temporal discounting.