Incidence trends and mortality rates of gastric cancer in Israel

Incidence trends and mortality rates of gastric cancer in Israel
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DOI:
10.1007/s10120-012-0155-4
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发表时间:
2013-04-01
期刊:
影响因子:
7.4
通讯作者:
Keinan-Boker, Lital
Keinan-Boker, Lital
中科院分区:
医学1区
文献类型:
--
作者:
Lavy, Ron;Kapiev, Andronik;Keinan-Boker, Lital

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胃癌是全球第四大常见恶性肿瘤。以色列胃癌的发病趋势和死亡率尚未得到深入研究。本研究的目的是尝试调查以色列不同民族的上述问题,这项回顾性研究是基于以色列国家癌症登记处和中央统计局的数据。本研究收集、总结和分析了这两个研究所发表的数据。以色列每年诊断出约650例新发胃癌病例。虽然我们注意到1990-2007年期间犹太人口的发病率有所下降(犹太男性和女性分别为每100,000人中有13.6-8.9例和6.75-5.42例病例),但阿拉伯人口的发病率却有所增加(男性和女性分别为每100,000人中有7.7-10.2例和3.7-4.2例病例)。在总人口中,每10 000例胃癌病例的经卫生组织调整的死亡率显著下降,从1990年的7.21例下降到2007年的5.46例。5年相对生存率显示男性和女性都略有增加。以色列犹太人和阿拉伯人胃癌的发病率和预后存在差异。以色列胃癌患者的严峻预后可能是由于以色列胃癌诊断的晚期阶段。
Gastric cancer is the fourth most common malignancy worldwide. The incidence trends and mortality rates of gastric cancer in Israel have not been studied in depth. The aim of our study was to try and investigate the aforementioned issues in Israel in different ethnic groups.This retrospective study is based on the data of The Israel National Cancer Registry and The Central Bureau of Statistics. Published data from these two institutes were collected, summarized, and analyzed in this study.Around 650 new cases of gastric cancer are diagnosed yearly in Israel. While we noticed a decline during the period 1990-2007 in the incidence in the Jewish population (13.6-8.9 and 6.75-5.42 cases per 100,000 in Jewish men and women, respectively), an increase in the Arab population was noticed (7.7-10.2 and 3.7-4.2 cases per 100,000 in men and women, respectively). Age-adjusted mortality rates per 10,000 cases of gastric cancer decreased significantly, from 7.21 in 1990 to 5.46 in 2007, in the total population. The 5-year relative survival showed a slight increase for both men and women.There is a difference in the incidence and outcome of gastric cancer between the Jewish and Arab populations in Israel. The grim prognosis of gastric cancer patients in Israel is probably due to the advanced stage at which gastric cancer is diagnosed in Israel.