Evaluation of variations in sensory and pain threshold assessments by electrocutaneous stimulation
Evaluation of variations in sensory and pain threshold assessments by electrocutaneous stimulation
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DOI：
10.1080/09593980590922307
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发表时间：
2005-06-01
影响因子：
2
通讯作者：
Svensson, Elisabeth
中科院分区：
文献类型：
--
作者：
Lund, Irene;Lundeberg, Thomas;Svensson, Elisabeth
评估的感觉和疼痛阈值可以改变，因此与持续疼痛相关的干扰。这种评估可以是日常临床评估感知疼痛的额外方法。为了研究这种程序的一天内和一天之间的测试-重测变异性，使用新开发的产生电皮肤刺激的仪器Pain Matcher（PM）来评估健康志愿者和疼痛患者的电感觉阈值（EST）和疼痛阈值（EPT）。所产生的数据被认为是有序的，并与秩不变的统计分析的属性，分析系统的分歧，偏差，和individualvariation.The百分比协议在+/-1 PM值EST的两组健康志愿者和疼痛患者分别为94%和92%，和EPT评估49%和78%，分别。EST评估的变异性可能可以通过轻微的偏差来解释，而两种情况之间的个体差异可以忽略不计。两组EPT均无偏倚，健康志愿者个体差异显著，疼痛患者个体差异可忽略不计。发现疼痛患者的EST与健康志愿者相比增加，p < 0.03，并且疼痛患者的EPT与健康志愿者相比降低，p < 0.001。本研究的结果表明，除了可能存在的偏倚外，EST和EPT的评估是稳定和可靠的。本研究所遵循的阈值评估程序可能是一个有价值的工具，在疼痛患者的感觉和疼痛评估的临床评价。
Assessed sensory and pain thresholds can change consequently to disturbances associated with ongoing pain. Such assessments could be an additional method in the daily, clinical evaluation of perceived pain. To study the test-retest variability within-day and between-day of such procedures a newly, developed instrument producing electrocutaneous stimulation, Pain Matcher (PM), was used to assess the electrical sensory thresholds (EST) and pain thresholds (EPT) in healthy volunteers and in patients with pain. The produced data were considered ordinal and analyzed with rank-invariant statistics with properties of analyzing systematic disagreement, bias, and individual variations.The percentage agreements within +/- 1PM value for EST were in the two groups of healthy volunteers and patients in pain 94% and 92%, and for EPT assessments 49% and 78%, respectively. The variability in the EST assessments is possibly, explained by a slight bias while the individual variations were negligible between the two occasions. The assessed EPT were unbiased in both groups while individual variations were significant among the healthy volunteers but negligible among the patients in pain. The EST was found to he increased in pain patients compared to healthy, volunteers, p < 0.03, and the EPT decreased in pain patients compared to healthy volunteers, p < 0.001. The results in this study indicate stable and reliable assessments of EST and EPT except for a possible bias.The threshold assessment procedure followed in this study may be a valuable tool in the clinical evaluation of sensory and pain assessments in pain patients.