Comparison of Bone-Conducted Cervical VEMPs Elicited by B71 and B81 Bone Vibrators
Comparison of Bone-Conducted Cervical VEMPs Elicited by B71 and B81 Bone Vibrators
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DOI：
10.1097/aud.0000000000000978
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发表时间：
2021-05-01
期刊：
影响因子：
3.7
通讯作者：
Clinard, Christopher
中科院分区：
文献类型：
--
作者：
Romero, Daniel J.;Piker, Erin G.;Clinard, Christopher
目的：多种刺激传递方法可以引发前庭肌源性诱发电位（VEMP）。当前的研究比较了两种不同临床骨振动器的骨传导 (BC) 颈椎 VEMP (cVEMP)。据推测，由于 B81 传感器在纯音测听应用中具有低频优势，因此可以更有效地产生更大的 BC-cVEMP 峰峰值。 设计：20 名 40 岁以下、没有听力或平衡障碍病史的年轻人参与了这项研究。使用两种临床骨传感器引出 BC cVEMP：Radioear B71 骨振动器和 Radioear B81 骨振动器。在数据收集之前，使用声学校准方法对两个传感器进行校准，并确定传感器的线性动态范围。参与者被要求坐下并匹配 100 μV 的固定肌电图 (EMG) 目标水平，同时使用 250、500 和 750 Hz 的刺激频率记录 BC cVEMP。结果：观察到 B71 和 B81 之间 250 和 750 Hz 的原始振幅存在统计学显着差异； B71 产生的峰峰值幅度比 B81 更大。在 500 Hz 时，B71 观察到较大的振幅，但结果没有统计学意义。 B71 在所有三个频率上产生的 cVEMP 阈值均显着降低。在这两个传感器中，与 250 和 750 Hz 相比，500 Hz 产生最大的峰峰值幅度。对于 250 和 500 Hz，峰峰值幅度没有增加到 55 dB nHL 以上，但幅度在 750 Hz 时继续增加。讨论：本研究发现 B71 和 B81 之间 BC-cVEMP 幅度和阈值存在统计显着差异，但结果与我们假设的不同。一般来说，与 B81 相比，B71 引起更大的 BC-cVEMP 振幅和更低的阈值。此外，500 Hz 被发现是两种 BC 换能器的最佳频率，这与之前的研究形成鲜明对比，表明较低的频率会产生较大的 BC-cVEMP 振幅。当观察个体幅度差异时，这些平均差异也可能具有临床意义。 500 Hz 处较大的峰峰值幅度可能部分归因于当前研究中使用的基础物理水平以及换能器的输出频谱，并且可以解释与 250 Hz 相比在 500 Hz 处观察到的更大的响应幅度。
Objective:A variety of stimulus delivery methods can elicit vestibular evoked myogenic potentials (VEMPs). The current study compared bone conduction (BC) cervical VEMPs (cVEMPs) across two different clinical bone vibrators. It was hypothesized that the B81 transducer would be more effective for producing larger BC-cVEMP peak to peak amplitudes due to its low-frequency advantages in pure-tone audiometry applications.Design:Twenty young adults under the age of 40 years with no reported history of hearing or balance disorders participated in the study. BC cVEMPs were elicited using two clinical bone transducers: the Radioear B71 bone vibrator and the Radioear B81 bone vibrator. Both transducers were calibrated using the acoustic method of calibration before data collection, and the linear dynamic range of the transducers was determined. Participants were asked to sit and match a fixed electromyography (EMG) target level of 100 mu V, while BC cVEMPs were recorded using stimulus frequencies of 250, 500, and 750 Hz.Results:Statistically significant differences in raw amplitude at 250 and 750 Hz between the B71 and B81 were observed; the B71 produced larger peak to peak amplitudes over the B81. At 500 Hz, larger amplitudes were observed with the B71, but results were not statistically significant. The B71 produced significantly lower cVEMP thresholds at all three frequencies. Across both transducers, 500 Hz produced the largest peak to peak amplitude compared with 250 and 750 Hz. Peak to peak amplitude did not increase above 55 dB nHL for 250 and 500 Hz, but amplitude continued to increase at 750 Hz.Discussion:The present study found statistically significant differences in BC-cVEMP amplitude and threshold between the B71 and B81, but results were not what we hypothesized. In general, the B71 elicited larger BC-cVEMP amplitudes and lower thresholds compared with the B81. Additionally, 500 Hz was found to be the best frequency for both BC transducers, contrasting previous studies suggesting lower frequencies yield larger BC-cVEMP amplitudes. It is possible that these average differences could also be clinically significant when looking at individual amplitude differences. Larger peak to peak amplitudes at 500 Hz may be partially due to the underlying physical levels used in the current study, as well as the output spectra of the transducers, and may explain the larger response amplitudes observed at 500 Hz compared with 250 Hz.