STUDIES ON LOW DOSE CHLOROQUINE THERAPY AND THE ACTION OF CHLOROQUINE IN SYMPTOMATIC PORPHYRIA
STUDIES ON LOW DOSE CHLOROQUINE THERAPY AND THE ACTION OF CHLOROQUINE IN SYMPTOMATIC PORPHYRIA
复制标题
小剂量氯喹治疗及其对症状性卟啉症的作用研究
DOI：
10.1111/j.1365-2133.1972.tb00316.x
复制
发表时间：
1972
影响因子：
10.3
通讯作者：
S. M. Joubert
中科院分区：
文献类型：
--
作者：
J. Taljaard;B. Shanley;E. Stewart;W. Deppe;S. M. Joubert
总结。8例有症状的卟啉症（迟发性皮肤卟啉症，PCT）患者在2至16周的时间内接受小剂量的硫酸氯喹治疗。一个良好的临床和生化反应，但一名患者，谁复发后，初步改善。仅1例患者出现急性不良反应。结论：小剂量氯喹治疗PCT安全有效。
Summary.— Eight patients with symptomatic porphyria (porphyria cutanea tarda symptomatica, PCT) were treated with small doses of chloroquin sulphate over periods ranging from 2 to 16 weeks. A good clinical and biochemical response was obtained in all but one patient, who relapsed after initial improvement. Manifestations of acute untoward reaction were seen in one patient only. It is concluded that low dose chloroquine therapy is both safe and effective in PCT.