HAIR CELL REGENERATION AFTER ACOUSTIC TRAUMA IN ADULT COTURNIX QUAIL
HAIR CELL REGENERATION AFTER ACOUSTIC TRAUMA IN ADULT COTURNIX QUAIL
复制标题
DOI：
10.1126/science.3381101
复制
发表时间：
1988-06-24
期刊：
影响因子：
56.9
通讯作者：
RUBEL, EW
中科院分区：
文献类型：
--
作者：
RYALS, BM;RUBEL, EW
本文研究了成年鹌鹑在声损伤后不同时间毛细胞的恢复情况。毛细胞最初的损失恢复到原来细胞数量的5%以内。在听觉损伤后注射氚标记的胸腺嘧啶核苷，以确定有丝分裂是否在毛细胞恢复中起作用。在声损伤后10天内，在毛细胞损失区的毛细胞和支持细胞的核内可见[~3H]胸腺嘧啶核苷的掺入。因此，毛细胞再生可以在胚胎末期有丝分裂后发生。
Recovery of hair cells was studied at various times after acoustic trauma in adult quail. An initial loss of hair cells recovered to within 5 percent of the original number of cells. Tritium-labeled thymidine was injected after this acoustic trauma to determine if mitosis played a role in recovery of hair cells. Within 10 days of acoustic trauma, incorporation of [3H]thymidine was seen over the nuclei of hair cells and supporting cells in the region of initial hair cell loss. Thus, hair cell regeneration can occur after embryonic terminal mitosis.