Severity of Chest Imaging is Correlated with Risk of Acute Neuroimaging Findings among Patients with COVID-19
Severity of Chest Imaging is Correlated with Risk of Acute Neuroimaging Findings among Patients with COVID-19
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DOI：
10.3174/ajnr.a7032
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发表时间：
2021-02-04
影响因子：
3.5
通讯作者：
Buch, K.
中科院分区：
文献类型：
--
作者：
Lang, M.;Li, M. D.;Buch, K.
背景和目的：COVID-19患者的严重呼吸窘迫与神经系统表现的发生率较高相关。我们的目的是调查2019冠状病毒病（COVID-19）患者胸部影像学检查结果的严重程度是否与急性神经影像学检查结果的风险相关。材料和方法：这项回顾性研究包括2020年3月3日至2020年5月6日期间在我院接受治疗的所有COVID-19患者，并在10？神经成像的日子使用先前验证的COVID-19自动神经网络算法（肺部X射线严重程度评分）评估胸片。使用基于每个肺叶受累的胸部CT严重程度评分系统对胸部CT进行分级。胸部影像学严重程度评分和急性神经影像学检查结果之间的关联进行了评估，采用多变量logistic regression.RESULTS：24的93例（26%）纳入研究的急性神经影像学检查结果，包括颅内出血（n = 7），梗死（n = 7），白质脑病（n = 6），或结果的组合（n = 4）。有急性神经影像学检查结果的患者的平均住院时间、重症监护室入院率和需要插管的患者比例显著高于无急性神经影像学检查结果的患者（P
BACKGROUND AND PURPOSE:Severe respiratory distress in patients with COVID-19 has been associated with higher rate of neurologic manifestations. Our aim was to investigate whether the severity of chest imaging findings among patients with coronavirus disease 2019 (COVID-19) correlates with the risk of acute neuroimaging findings.MATERIALS AND METHODS:This retrospective study included all patients with COVID-19 who received care at our hospital between March 3, 2020, and May 6, 2020, and underwent chest imaging within 10?days of neuroimaging. Chest radiographs were assessed using a previously validated automated neural network algorithm for COVID-19 (Pulmonary X-ray Severity score). Chest CTs were graded using a Chest CT Severity scoring system based on involvement of each lobe. Associations between chest imaging severity scores and acute neuroimaging findings were assessed using multivariable logistic regression.RESULTS:Twenty-four of 93 patients (26%) included in the study had positive acute neuroimaging findings, including intracranial hemorrhage (n = 7), infarction (n = 7), leukoencephalopathy (n = 6), or a combination of findings (n = 4). The average length of hospitalization, prevalence of intensive care unit admission, and proportion of patients requiring intubation were significantly greater in patients with acute neuroimaging findings than in patients without them (P