Association between overactive bladder and peri-menopause syndrome: a cross-sectional study of female physicians in China
Association between overactive bladder and peri-menopause syndrome: a cross-sectional study of female physicians in China
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DOI：
10.1007/s11255-015-0948-6
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发表时间：
2015-05-01
影响因子：
2
通讯作者：
Bai, Wenpei
中科院分区：
文献类型：
--
作者：
Chen, Yuke;Yu, Wei;Bai, Wenpei
为了解我国围绝经期女性医师膀胱过度活动症（OAB）与围绝经期综合征（PMpS）的关系，对北京大学三所直属医院的中年女性医师进行问卷调查，了解围绝经期症状和OAB状况。我们使用膀胱过度活动症症状评分（OABSS）来验证OAB的症状，并使用改良Kupperman绝经指数（KMI）来评估PMpS。平均年龄为47.1 +/- A 5.4岁。总体而言，7.4%的受访者患有OAB，22.6%患有PMpS。OAB的严重程度与OAB和PMpS的患病率呈显著正相关。PMpS妇女（KMI > 15）的OAB患病率显著增加（18.99vs.4.44%; P = 0. 000）。PMpS女性的平均OABSS为2.67 +/-A2.15，而无PMpS女性为1.46 +/-A1.50。OAB女性的平均KMI评分为16.04 +/- A 10.1，而非OAB女性为9.50 +/- A 8.13（P = 0.000）。多因素Logistic回归分析结果显示，只有BMI和PMpS是OAB的独立危险因素。在中国，有更年期症状的女性医生OAB患病率更高，症状更严重。
To determine the detailed association between overactive bladder (OAB) and peri-menopause syndrome (PMpS) in Chinese female physicians of peri-menopausal age.Data for this study were collected by administering questionnaires eliciting general information (peri-menopausal symptoms and OAB status) to middle-aged female physicians, from the directly affiliated three hospitals of Peking University in China. We used the overactive bladder symptom score (OABSS) to verify the symptoms of OAB and the modified Kupperman menopausal index (KMI) to assess PMpS.Three hundred fifty-one questionnaires were finally evaluated. The average age was 47.1 +/- A 5.4 years. Overall, 7.4 % of respondents had OAB and 22.6 % had PMpS. There was a significant positive correlation between the severity of OAB and prevalence of OAB and PMpS. The prevalence of OAB in women with PMpS (KMI > 15) was significantly increased (18.99 vs. 4.44 %; P = 0.000). The average OABSS in women with PMpS was 2.67 +/- A 2.15, compared with 1.46 +/- A 1.50 in women without PMpS. The average KMI score in women with OAB was 16.04 +/- A 10.1, compared with 9.50 +/- A 8.13 in women without OAB (P = 0.000). Multivariate logistic regression analysis results showed that only BMI and PMpS were independent risk factors for OAB.In China, female physicians with menopausal symptoms tend to have a higher prevalence of OAB and more severe symptoms of OAB.