Conditioned aversion to saccharin resulting from exposure to gamma radiation.
Conditioned aversion to saccharin resulting from exposure to gamma radiation.
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DOI：
10.1126/science.122.3160.157
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发表时间：
1955-07
期刊：
影响因子：
56.9
通讯作者：
J. Garcia;D. J. Kimeldorf;R. A. Koelling
中科院分区：
文献类型：
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作者：
J. Garcia;D. J. Kimeldorf;R. A. Koelling
同时暴露于伽马辐射和糖精味饮用水的动物组的U '30。表明所有动物都尝到了辐射暴露期间呈现给它们的液体。在辐射后第1天，在暴露期间接受水的组仅给予糖精溶液6小时，其他组仅接受水以平衡糖精的经验。在辐射后第2天，糖精溶液和水同时可供每只动物使用6小时。从辐射后第3天开始，每只动物连续获得糖精溶液和水。以24小时间隔测量消耗量。在辐射后偏好测试期间，每天颠倒饮料瓶以避免刻板的位置反应。位置的影响是不可检测的糖精偏好时，明显高或低。然而，当分数在中性偏好范围内时，可以检测到位置效应。为了尽量减少位置对评分的影响，将每只动物的每个连续的左侧和右侧测量对组合，并报告48小时值。所用的糖精偏好评分是比率的商
U'30 for animal groups exposed concurrently to gamma radiation and saccharin-flavored drinking water. indicated that all animals had tastedl the fluid presented to them during radiation exposure. On day 1 postirradiation, the groups that had received water during exposure were presented with the saccharin soltation only for 6 hr, and the other groups received water only in order to equalize the experience with saccharin. On day 2 postirradiation, saccharin solution and water were simultaneously avail-able to each animal for a 6-hr period. Beginning with the day 3 postirradiation, both saccharin solution and water were available to each animal on a continuous basis. Measurements of consumption were made at 24-hr intervals. During the postirradiation preference testing period, the drinking bottles were reversed daily to avoid a stereotyped position response. An effect of position was not detectable when the saccharin preference was distinctively high or low. However, when the scores were in the neutral range of preference, a position effect could be detected. In order to minimize the effect of position on the scores, each consecutive left and right measurement pair are combined for each animal, and 48-hr values are reported. The saccharin preference score utilized is the quotient for the ratio