Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.
Underscoring the influence of inorganic chemistry on nuclear imaging with radiometals.
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DOI：
10.1021/ic401607z
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发表时间：
2014-02-17
影响因子：
4.6
通讯作者：
Lewis JS
中科院分区：
文献类型：
--
作者：
Zeglis BM;Houghton JL;Evans MJ;Viola-Villegas N;Lewis JS
在过去的几十年里，放射性核素已经从基本上是深奥的实验技术发展成为医学诊断不可或缺的组成部分。在某种程度上，推动这一转变的是生物医学工程、核医学和癌症生物学相互必需的进步。无机化学在促进新型放射性示踪剂发展方面的开创性作用有些默默无闻。在这方面，这篇论坛文章的目的是通过详细介绍五种金属基显像剂：64Cu-ATSM， 68Ga-DOTATOC, 89Zr-transferrin， 99mTc-sestamibi和99mTc-colloids的发展，更明显地突出无机化学对核成像的重要贡献。在结语部分，将讨论实验室内外的几个未满足的需求，以促进无机化学家和成像社区之间的对话。
Over the past several decades, radionuclides have matured from largely esoteric and experimental technologies to indispensible components of medical diagnostics. Driving this transition, in part, have been mutually necessary advances in biomedical engineering, nuclear medicine, and cancer biology. Somewhat unsung has been the seminal role of inorganic chemistry in fostering the development of new radiotracers. In this regard, the purpose of this Forum Article is to more visibly highlight the significant contributions of inorganic chemistry to nuclear imaging by detailing the development of five metal-based imaging agents: 64Cu-ATSM, 68Ga-DOTATOC, 89Zr-transferrin, 99mTc-sestamibi, and 99mTc-colloids. In a concluding section, several unmet needs both in and out of the laboratory will be discussed to stimulate conversation between inorganic chemists and the imaging community.
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影响因子：
2.8
作者：
Amin, S;Marks, C;Morrow, JR
通讯作者：
Morrow, JR
影响因子：
4.9
作者：
Alazraki, NP;Eshima, D;Taylor, AT
通讯作者：
Taylor, AT
影响因子：
15
作者：
Alberto, R;Schibli, R;Kaden, TA
通讯作者：
Kaden, TA
DOI：
10.1007/s00259-006-0317-x
发表时间：
2007-07-01
影响因子：
9.1
作者：
Antunes, P.;Ginj, M.;Maecke, H.
通讯作者：
Maecke, H.
影响因子：
4.3
作者：
Abiraj, Keelara;Mansi, Rosalba;Maecke, Helmut R.
通讯作者：
Maecke, Helmut R.